Results 1 to 10 of about 24,309,158 (381)
Endothelin-1 and antiangiogenesis [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2016 Antiangiogenesis, targeting vascular endothelial growth factor (VEGF), has become a well-established treatment for patients with cancer. This treatment is associated with nitric oxide (NO) suppression and a dose-dependent activation of the endothelin system, resulting in preeclampsia-like features, particularly hypertension and renal injury. Studies in
Lankhorst, Stephanie +2 more
openaire +3 more sources
Definitions, 2020 Endothelin-1 receptor (427 aa, ~49 kDa) is encoded by the human EDNRA gene. This protein is a multipass transmembrane protein that is a receptor for endothelin-1 protein and plays a role in G protein-mediated signal transduction.
openaire +2 more sources
Journal of Ophthalmology, 2016 Purpose. The aim of this meta-analysis was to clarify the association between the plasma endothelin-1 level and the risks of normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG). Methods.
Shengjie Li +3 more
doaj +2 more sources
Endothelin-1 in systemic sclerosis
Reumatismo, 2011 We evaluated endothelin-1 (ET-1) plasma levels in patients affected by primary Raynaud’s phenomenon (PRP), as well as in patients with systemic sclerosis (SSc) and secondary Raynaud’s phenomenon (SRP).
C. Pizzorni +3 more
doaj +6 more sources
The FASEB Journal, 2010 Over two decades of research have demonstrated that the peptide hormone endothelin‐1 (ET‐1) plays multiple, complex roles in cardiovascular, neural, pulmonary, reproductive, and renal physiology. Differential and tissue‐specific production of ET‐1 must be tightly regulated in order to preserve these biologically diverse actions ...
Lisa R, Stow +3 more
openaire +4 more sources
Endothelin-1 in systemic sclerosis
Indian Dermatology Online Journal, 2012 Introduction: Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and organ damage. Endothelin-1 (ET-1) plays a role in skin fibrosis.
Mehrdad Aghaei +7 more
doaj +3 more sources
Adverse Childhood Experiences Are Associated With Detrimental Hemodynamics and Elevated Circulating Endothelin-1 in Adolescents and Young Adults [PDF]
HYPERTENSION, 2014 Shaoyong Su +7 more
openalex +2 more sources