Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims To evaluate whether type 2 diabetes status modifies the efficacy and safety of combining zibotentan (zibo), a selective endothelin receptor antagonist, and dapagliflozin (dapa) compared to placebo plus dapagliflozin in individuals with chronic kidney disease (CKD).
Victor Wasehuus +7 more
wiley +1 more source
Differential Vascular Sensitivity to Luminally and Adventitially Applied Endothelin-1
, 1989 Ulrich Pohl, Rudi Busse
openalex +1 more source
Haemodynamic effects of human α‐calcitonin gene‐related peptide following administration of endothelin‐1 or NG‐nitro‐
, 1991 Sheila M. Gardiner +5 more
openalex +1 more source
European Journal of Clinical Investigation, EarlyView.This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano +3 more
wiley +1 more source
Pulmonary arterial hypertension outcomes upon endothelin-1 receptor antagonist switch to macitentan [PDF]
, 2019 Objectives: To assess whether switching patients with suboptimally controlled pulmonary arterial hypertension from bosentan or ambrisentan to macitentan would improve six-minute walk test (6MWT) distance and World Health Organization functional class ...
Gabbay, Eli +3 more
core +1 more source
Effect of Endothelin-1 on Arterioles and Venules in vivo
, 1989 Zuleica Bruno Fortes +2 more
openalex +1 more source
Effects of KRN2391, nicorandil and diltiazem on the changes in the electrocardiogram caused by endothelin‐1 in anaesthetized rats [PDF]
, 1993 Katsuhiko Harada +5 more
openalex +1 more source
Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
PROTEOMICS, EarlyView.
Paul Perco +7 more
wiley +1 more source
WNT5a export onto extracellular vesicles studied at single‐molecule and single‐vesicle resolution
The FEBS Journal, EarlyView.WNT signaling, which orchestrates tissue development and homeostasis, is mediated by hydrophobic WNT proteins traveling from secreting to receiving cells on various carriers. Here, fusion constructs of fluorescent proteins with WNT5a were developed and functionally validated.
Antonia Schubert +16 more
wiley +1 more source
Endothelin-1-Induced Contractions of Vascular and Tracheal Smooth Muscle
, 1989 Neil C Turner +2 more
openalex +1 more source