Results 241 to 250 of about 24,309,158 (381)

Endothelin-1 and its role in the pathogenesis of infectious diseases.

Life Science, 2014
B. Freeman, F. Machado, H. Tanowitz, M. Desruisseaux   +3 more
semanticscholar   +1 more source

Network and Gene Set Enrichment Analysis of Adipokine Drivers of Prostate Cancer; Unravelling the Mechanistic Link Between Excess Adiposity and Prostate Cancer Risk

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Adiposity‐Based Chronic Disease (ABCD), a novel model housing obesity, insulin resistance, and adipokine‐related inflammation, increases the risk of aggressive prostate cancer (PCa), posttreatment PCa recurrence, and PCa mortality. This paper provides a new network analysis of relevant metabolic drivers to provide insight into the ...
Zachary Dovey, Elena Tomas Bort, Jeffrey I. Mechanick   +2 more
wiley   +1 more source

Autoantibodies directed against the angiotensin II type 1 receptor and the endothelin-1 type A receptor in patients with systemic sclerosis. [PDF]

RMD Open
van der Wouden KE, Ahmed S, van Oostveen WM, Hoekstra EM, Liem SIE, Huizinga TWJ, Toes REM, Voskuyl AE, Riemekasten G, Fehres CM, Vonk M, de Vries-Bouwstra JK.   +11 more
europepmc   +1 more source

Does endothelin-1 reduce superior mesenteric artery blood flow velocity in preterm neonates? [PDF]

, 1999
F J Weir, Arne Ohlsson, Katherine Fong, Kofi Amankwah, Flavio Coceani   +4 more
openalex   +1 more source

Design and Synthesis of Novel Purine Analogues as Potential IL‐1β Inhibitors Targeting Vascular Inflammation

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Initial screening of the synthesized compounds revealed that compounds MK175 and MK169 inhibited LPS‐induced IL‐1β release in human aortic smooth muscle cells. ABSTRACT Proinflammatory cytokine interleukin (IL)‐1β is a key mediator of the inflammatory response in atherosclerosis.
Dimitra T. Pournara, Theano Fotopoulou, Geena Paramel, Madelene Lindkvist, Magnus Grenegård, Karin Fransén, Maria Koufaki   +6 more
wiley   +1 more source

Endothelin-1 triggers oxidative stress and cytokine release in human microglia cells through ETRB-dependent mechanisms. [PDF]

Front Cell Neurosci
Inostroza-Nieves Y, Bou S, Alvarado J, Capo-Ruiz D, Garcia J, Moliere JP, Arenas CP.   +6 more
europepmc   +1 more source

Circulating markers of inflammation are not elevated in the early development of insulin resistance

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1569-1572, February 2026.
Dominik Tischer, Sarah J. Blackwood, Marjan Pontén, Marcus Moberg, Abram Katz   +4 more
wiley   +1 more source

A Case of Atrial Septal Defect Unveiled by the Treatment for Pulmonary Arterial Hypertension

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT We present a case of a 51‐year‐old woman with atrial septal defect (ASD) masked by pulmonary arterial hypertension (PAH). Three months after PAH treatment with a combination of endothelin receptor antagonist and phosphodiesterase five inhibitor, the transthoracic echocardiography revealed left‐to‐right shunting through a secundum ASD.
Takaaki Fujii, Sayuri Yamabe, Yoshiro Tsuruta, Yu Kawada, Tatsuya Mizoguchi, Masashi Yokoi, Kento Mori, Tsuyoshi Ito, Shuichi Kitada, Toshihiko Goto, Shigefumi Fukui, Hideo Izawa, Yoshihiro Seo   +12 more
wiley   +1 more source

Endothelin (ET)‐1 and ET‐3 promote expression ofc‐fosandc‐junin human choriocarcinoma via ET_Breceptor‐mediated G_i‐ and G_q‐pathways and MAP kinase activation [PDF]

, 2008
Anamaria Rauh, Werner Windischhofer, Alexander Kovacevic, Trevor DeVaney, Eveline Huber, Michaela Semlitsch, H‐J Leis, Wolfgang Sattler, Ernst Malle   +8 more
openalex   +1 more source

Edible Seeds in the Fight Against Hypertension: A Review of In Vitro, In Vivo, and Clinical Evidences With a Mechanistic Insight of Bioactive Compounds

Food Frontiers, Volume 7, Issue 1, January 2026.
The presented review provides the potential antihypertensive benefits of traditionally employed edible seeds, presenting new perspectives and avenues for future research. ABSTRACT Hypertension, often referred to as a silent killer, is responsible for 7.5 million deaths, representing approximately 12.8% of all global mortality.
Jinmin Shi, Mohamad Fawzi Mahomoodally, Ahmed Abduljalal Abduljabbar, Ruttun Bushra Umme Zainab, Katharigatta N. Venugopala, Gokhan Zengin, Sakina Yagi, Meng‐Yao Li, Xuebo Hu   +8 more
wiley   +1 more source