Results 261 to 270 of about 23,747,035 (396)

Arrestin‐centred interactions at the membrane and their conformational determinants

British Journal of Pharmacology, Volume 182, Issue 14, Page 3135-3150, July 2025.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals   +3 more
wiley   +1 more source

Prediction of Japan Score and Society of Thoracic Surgeons Risk Scores for Patients Undergoing Cardiovascular Surgery by Serum Growth Differentiation Factor-15 and Endothelin-1 Levels. [PDF]

Cureus
Fukuda T, Kato T, Kanazawa Y, Hirai R, Ishizaka H, Tan H, Shibasaki I, Fukuda H, Toyoda S, Nakajima T.   +9 more
europepmc   +1 more source

ENDOTHELIN-1 IN BRONCHOALVEOLAK LAVAGE DURING REJECTION OF ALLOTRANSPLANTED LUNGS

, 1994
Henrik Scherstén, Pertti Aarnio, John Burnett, Christopher G.A. McGregor, Virginia M. Miller   +4 more
openalex   +1 more source

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

Proceedings of the National Academy of Sciences of the United States of America, 2013
Carlene D. Moore, F. Cevikbas, H. Pasolli, Yong Chen, Wei-dong Kong, C. Kempkes, P. Parekh, S. Lee, Nelly-Ange Kontchou, I. Yeh, N. Jokerst, E. Fuchs, M. Steinhoff, Wolfgang Liedtke   +13 more
semanticscholar   +1 more source

Role of epicardial adipose tissue in heart failure with preserved ejection fraction: An emerging molecular mechanism and therapeutic potential

Obesity Reviews, Volume 26, Issue 7, July 2025.
Summary With the evolving landscape of diseases, heart failure with preserved ejection fraction (HFpEF) now encompasses more than half of all heart failure patients. This condition is clinically diverse, involving multiple organ systems and often occurring alongside the aging process.
Zhongwen Qi, Dan Wu, Zhipeng Yan, Qing Wang, Yiming Li, Junnan Zhao, Fengqin Xu   +6 more
wiley   +1 more source

Kinetics of endothelin-1 and effect selective ET_A antagonism on ET_B activation: a mathematical modeling analysis. [PDF]

Front Pharmacol
Hallow KM, Greasley PJ, Heerspink HJL, Yu H.   +3 more
europepmc   +1 more source

Reduction in Local Cerebral Blood Flow Induced by Endothelin-1 Applied Topically to the Middle Cerebral Artery in the Rat

, 1991
Michael J. Robinson, I. Mhairi Macrae, Mary E. Todd, James Reid, James McCulloch   +4 more
openalex   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

Advanced Science, Volume 12, Issue 22, June 12, 2025.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang, Shukui Zhang, Huiyang Jia, Fen Ji, Jianwei Jiao   +4 more
wiley   +1 more source

Involvement of endothelins, peptides with potent vasoactive properties, in HIV-1 encephalopathy [PDF]

, 1992
Bogner, Johannes R., Clouse, K. A., Ehrenreich, H., Geier, Stephan A., Goebel, Frank-Detlef, Hippius, Hanns, Klauß, Volker, Kronawitter, Ursula, Rieckmann, P., Rolinski, B., Sinowatz, F., Weis, Serge   +11 more
core   +1 more source

Endothelin-1-Induced Persistent Ischemia in a Chicken Embryo Model. [PDF]

Bio Protoc
Kumari N, Prakash R, Siddiqui AJ, Waseem A, Khan MA, Raza SS.   +5 more
europepmc   +1 more source