Endothelins as mediators in the modulation of cardiac performance [PDF]
Praxis Medica, 2014 The role of endothelin in cardiovascular physiology and pathophysiology has been undeniable ever since its discovery. Endothelins in the heart are important for the development, growth and remodeling, as well as for the control of contractility and ...
Smiljić Sonja +4 more
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Serum endothelin-1 level positively correlates with waist and hip circumferences in stable coronary artery disease patients [PDF]
Reviews in Cardiovascular Medicine, 2021 Central obesity is associated with increased level and activity of endothelin-1. The waist and hip circumferences are simple indicators of central obesity.
Anggoro Budi Hartopo +3 more
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Endothelium-derived endothelin-1 [PDF]
Pflügers Archiv - European Journal of Physiology, 2009 One year after the revelation by Dr. Furchgott in 1980 that the endothelium was obligatory for acetylcholine to relax isolated arteries, it was clearly shown that the endothelium could also promote contraction. In 1988, Dr. Yanagisawa's group identified endothelin-1 (ET-1) as the first endothelium-derived contracting factor.
Thorin, Eric, Webb, David J.
openaire +3 more sources
Vestnik Dermatologii i Venerologii, 2021 Background. Atopic dermatitis is a chronic multifactorial dermatosis with a complex pathophysiological basis. One of the poorly studied links in the pathogenesis of the disease is endothelin-1.
Irina V. Kibalina, Namzhil N. Tsybikov
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Frontiers in Immunology, 2023 Major Histocompatibility Complex (MHC) molecules have been proposed to play a role in Sickle Cell Disease (SCD) pathophysiology. Endothelial cells express MHC molecules following exposure to cytokines.
Yaritza Inostroza-Nieves +6 more
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Immunohistochemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ [PDF]
Journal of Dentistry, 2023 Statement of the Problem: Enamel organ (EO) is an ectodermal derived structure, which is involved in the different aspects of tooth development. Tooth development shares the same regulatory molecules and genes expressed in other developing organs ...
Soussan Irani +2 more
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Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin [PDF]
, 2010 Background: Changes in cellular phenotype result from underlying changes in mRNA transcription and translation. Endothelin-1 stimulates cardiomyocyte hypertrophy with associated changes in mRNA/protein expression and an increase in the rate of protein ...
Clerk, Angela +5 more
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Endocrine and Metabolic Science, 2023 Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation.
Joshua J. Joseph +7 more
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Different role of endothelin ETA and ETB receptors and endothelial modulators in diabetes-induced hyperreactivity of the rabbit carotid artery to endothelin-1 [PDF]
, 2004 The influence of diabetes on regulatory mechanisms and specific receptors implicated in the contractile response of isolated rabbit carotid arteries to endothelin-1 was examined. Endothelin-1 induced a concentration-dependent contraction that was greater
Alabadí Ferrer, José Antonio +4 more
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Contribution of endothelin receptors and cyclooxygenase-derivatives to the altered response of the rabbit renal artery to endothelin-1 in diabetes [PDF]
, 2006 The influence of diabetes on regulatory mechanisms and specific receptors implicated in the response of isolated rabbit renal artery to endothelin-1 was examined. Endothelin-1 induced a concentration-dependent contraction that was less potent in arteries
Alabadí Ferrer, José Antonio +4 more
core +2 more sources