Results 81 to 90 of about 23,747,035 (396)
Volume expansion enhances plasma endothelin-1 [PDF]
, 2017 We hypothesized that acute volume expansion by saline infusion triggers the release of endothelin-1. Bolus intravenous saline infusion (8 mL/min) in six groups of conscious Wistar rats and spontaneously hypertensive rats did not change mean arterial ...
Abdel-Sayed, Saad +2 more
core
Endothelin and the ischaemic heart [PDF]
, 2005 Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
Kane, K.A., McCabe, C., Wainwright, C.L.
core +1 more source
Chinese Journal of Lung Cancer, 2008 Background and objective Endothelin-1 (ET-1) is a potent mitogen involved in cell growth in human lung adenocarcinoma cells SPC-A1. The increase in intracellular free calcium ([Ca2+]i) plays a great role in this process.
Juan ZHOU +3 more
doaj
Endocrine and Metabolic Science, 2023 Introduction: African Americans (AAs) have the highest prevalence of hypertension among United States racial/ethnic groups. Regulators of blood pressure, such as aldosterone and endothelin-1, impact glucose regulation.
Joshua J. Joseph +7 more
doaj
Arrhythmogenic action of endothelin-1 [PDF]
Cardiovascular Research, 2000 Dear Editor, It was highly interesting to read the ‘Letter to the Editor’ by Duru et al. [1] regarding the arrhythmogenic action of endothelin-1 (ET-1). ET-1 is supposed to act as a paracrine hormone released due to stretch or myocardial ischaemia in vivo. ET-1 prolonged action potential duration with early afterdepolarization (EAD) formation in right
Béla Merkely +5 more
openaire +3 more sources
Arthritis &Rheumatology, EarlyView.Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen +8 more
wiley +1 more source
Murine study of portal hypertension associated endothelin-1 hypo-response [PDF]
, 2015 AIM: To investigate endothelin-1 hypo-responsive associated with portal hypertension in order to improve patient treatment outcomes. METHODS: Wild type, eNOS(-/-) and iNOS(-/-) mice received partial portal vein ligation surgery to induce portal ...
Maluccio, Mary +2 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato +9 more
wiley +1 more source
Inverse correlation between endothelin-1-induced peripheral microvascular vasoconstriction and blood pressure in glaucoma patients [PDF]
, 2018 • Background: The potent vasoconstrictor peptide endothelin-I has been shown to participate in the control of peripheral vascular tone and in the regulation of ocular perfusion.
Flammer, Josef +5 more
core
Egyptian Journal of Chest Disease and Tuberculosis, 2012 Study objective: This study analyses for the first time endothelin-1 (ET-1) level, and gene polymorphisms for endothelin-1 (EDN1 gene) in patients with pulmonary arterial hypertension (PAH) in Egypt. Design: Cross-sectional study.
Emad Ibrahim +2 more
doaj +1 more source