Results 131 to 140 of about 90,498 (305)

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani   +5 more
wiley   +1 more source

Endothelial dysfunction role in atherosclerosis pathogenesis

open access: yesКардиоваскулярная терапия и профилактика, 2006
According to modern views, the key component in atherosclerosis pathogenesis is endothelial dysfunction (ED), manifesting in dysbalance between main endothelial functions: vasodilatation and vasoconstriction, proliferation inhibition and promotion ...
E. N. Vorobyeva   +4 more
doaj  

Effects of Marathon Running on Cardiac Markers and Endothelin-1 in EIH Athletes [PDF]

open access: bronze, 2013
Y. Kim   +9 more
openalex   +1 more source

Longitudinal sex differences in cerebrovascular ageing in older adults: results from the brain in motion study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Longitudinal assessment of sex differences in cerebrovascular ageing over a ∼6 year period: the Brain in Motion study. Cerebrovascular function was assessed at baseline (T1) and at a follow‐up (T2) ∼6 years later, at rest, during euoxic hypercapnia and while engaging in submaximal exercise. Over the follow‐up period females had a
Connor Snow   +10 more
wiley   +1 more source

Adipocyte endothelin B receptor activation inhibits adiponectin production and causes insulin resistance in obese mice [PDF]

open access: bronze
Osvaldo Rivera‐Gonzalez   +9 more
openalex   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò   +18 more
wiley   +1 more source

The Influence of PAR 1 and Endothelin 1 on the Course of Specific Kidney Diseases. [PDF]

open access: yesJ Clin Med
Szymczak M   +11 more
europepmc   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey   +5 more
wiley   +1 more source

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