Results 201 to 210 of about 90,498 (305)

DNA methylation of the endothelin receptor B makes blue fish yellow. [PDF]

open access: yesNat Commun
Fang W   +6 more
europepmc   +1 more source

Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1−ALK1 Signaling During Angiogenesis

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Endothelial cells within chronic pulmonary artery thrombi in CTEPH overexpress transmembrane protein 100 (TMEM100), an activin A receptor‐like kinase 1 (ACVRL1 or ALK1) signaling‐dependent gene, and TGFβ1 upregulated TMEM100 transcription in healthy lung ECs.
Magdalena L. Bochenek   +10 more
wiley   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

open access: yesThe Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida   +4 more
wiley   +1 more source

Current Knowledge About Aprocitentan in Hypertension. [PDF]

open access: yesInt J Mol Sci
Bank-Mikkelsen EM, Grimm D, Wehland M.
europepmc   +1 more source

UPREGULATION OF ENDOTHELIN (ETA AND ETB) RECEPTORS AND DOWN REGULATION OF NITRIC OXIDE SYNTHASE IN THE DETRUSOR OF A RABBIT MODEL OF BLADDER OUTLET OBSTRUCTION

open access: hybrid, 1999
Cecil S. Thompson   +5 more
openalex   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 16-26, January 2026.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle   +3 more
wiley   +1 more source

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