Results 201 to 210 of about 162,472 (321)

Endothelin A receptor in nociceptors is essential for persistent mechanical pain in a chronic pancreatitis of mouse model. [PDF]

World J Gastroenterol
Wang B, Ge JY, Wu JN, Xu JH, Cao XH, Chang N, Zhou X, Jing PB, Liu XJ, Wu Y.   +9 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Aprocitentan: New insights

Frontiers in Cardiovascular Medicine, 2022
Fahimeh Varzideh, Fahimeh Varzideh, Urna Kansakar, Urna Kansakar, Stanislovas S. Jankauskas, Stanislovas S. Jankauskas, Gaetano Santulli, Gaetano Santulli   +7 more
doaj   +1 more source

Effect of Endothelin-1 on Arterioles and Venules in vivo

, 1989
Zuleica Bruno Fortes, Gilberto De Nucci, J. Garcia-Leme   +2 more
openalex   +1 more source

Advancing antihypertensive drug development

British Journal of Pharmacology, Volume 182, Issue 15, Page 3389-3410, August 2025.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu, Yanrong Liu, Fozia Zahir Ahmed, Xin Wang, Darren Green, Hongyuan Zhang   +5 more
wiley   +1 more source

AAV2-driven endothelin induces chronic reduced retinal blood flow/retinal ganglion cell loss in rats. [PDF]

Life Sci Alliance
Shi G, Sato K, Takahashi N, Ohno-Ohishi M, Murayama N, Yamaguchi C, Saigusa D, Nakazawa T.   +7 more
europepmc   +1 more source

ENDOTHELIN-INDUCED STIMULATION OF DNA SYNTHESIS IN VASCULAR SMOOTH MUSLCE CELLS

, 1989
Toshio Nakaki, Misa Nakayama, Satoshi Yamamoto, Ryuichi Kato   +3 more
openalex   +1 more source

Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells. [PDF]

, 1990
Yoh Takuwa, Yoshitoshi Kasuya, Noriko Takuwa, Masatoshi Kudo, Masashi Yanagisawa, K Goto, Takao Masaki, Kamejiro Yamashita   +7 more
openalex   +1 more source

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

Journal of Sleep Research, Volume 34, Issue 4, August 2025.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher, Philip I. Aaronson, Jesús Prieto‐Lloret   +4 more
wiley   +1 more source

Endothelin-1 Participates in the Pathogenesis of Prurigo Nodularis by Promoting NGF Expression via Endothelial Receptor B in Epidermal Keratinocytes and Dorsal Root Ganglion Cells. [PDF]

Allergy
Wong LS, Yang JL, Yen YT, Lee CH, Yang JH.   +4 more
europepmc   +1 more source