Endothelin A receptor in nociceptors is essential for persistent mechanical pain in a chronic pancreatitis of mouse model. [PDF]
Wang B+9 more
europepmc +1 more source
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani+5 more
wiley +1 more source
Effect of Endothelin-1 on Arterioles and Venules in vivo
Zuleica Bruno Fortes+2 more
openalex +1 more source
Advancing antihypertensive drug development
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu+5 more
wiley +1 more source
AAV2-driven endothelin induces chronic reduced retinal blood flow/retinal ganglion cell loss in rats. [PDF]
Shi G+7 more
europepmc +1 more source
ENDOTHELIN-INDUCED STIMULATION OF DNA SYNTHESIS IN VASCULAR SMOOTH MUSLCE CELLS
Toshio Nakaki+3 more
openalex +1 more source
Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells. [PDF]
Yoh Takuwa+7 more
openalex +1 more source
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez+4 more
wiley +1 more source
Endothelin-1 Participates in the Pathogenesis of Prurigo Nodularis by Promoting NGF Expression via Endothelial Receptor B in Epidermal Keratinocytes and Dorsal Root Ganglion Cells. [PDF]
Wong LS+4 more
europepmc +1 more source