Results 231 to 240 of about 90,498 (305)

Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao, Rui Luo, Ying Deng, Hongqiu Yang, Yu Du   +4 more
wiley   +1 more source

The multifactorial role of HDAC9 at the maternal-fetal interface in the pathogenesis of preeclampsia. [PDF]

Clin Sci (Lond)
Opichka MA, McIntosh JJ, Grobe JL.
europepmc   +1 more source

Acute Rejection With DSA‐Negative Severe Microvascular Inflammation in a Kidney Transplant Recipient With an Isolated DPB1*04‐Mismatch Successfully Stabilised With Daratumumab

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl, Maike Büttner‐Herold, Markus Götz, Markus Luber, Bernd Spriewald, Michael Oellerich, Julia Beck, Bernhard Banas, Daniel Zecher   +8 more
wiley   +1 more source

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

Experimental Physiology, Volume 111, Issue 1, Page 257-269, 1 January 2026.
Schematic illustration of the experimental design. This study investigated the role of Orexin A in the pathogenesis of ischemic stroke at high altitude. Abstract Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression.
Minxia Zhu, Xu Guo, Jing Guo, Zhaojun Zhang, Kexin Zhang, Yaqi Lei, Yuhe Wang, Haoshuang Zhan   +7 more
wiley   +1 more source

The Biomarker Galaxy: Big Endothelin-1 Joins the Expanding Universe of Heart Failure Prognostication. [PDF]

Korean Circ J
Cho DH.
europepmc   +1 more source

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from DAPA‐CKD and FIGARO‐DKD

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 750-753, January 2026.
Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink   +4 more
wiley   +1 more source

Dietary flavanols preserve upper‐ and lower‐limb endothelial function during sitting in high‐ and low‐fit young healthy males

The Journal of Physiology, Volume 604, Issue 1, Page 145-171, 1 January 2026.
Abstract figure legend Schematic indicating the design of an acute randomised, counterbalanced, double‐blinded, cross‐over, placebo‐controlled human study in which 20 high‐fit males and 20 low‐fit males consumed either a low‐flavanol (5.6 mg) or a high‐flavanol (695 mg) cocoa drink prior to a 2 h uninterrupted sitting bout.
Alessio Daniele, Samuel J. E. Lucas, Catarina Rendeiro   +2 more
wiley   +1 more source

Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder that significantly increases cardiovascular disease (CVD) risk in women. While insulin resistance and dyslipidemia are established contributors, growing evidence highlights mitochondrial dysfunction and chronic low‐grade inflammation as central drivers of cardiovascular ...
Olabimpe Caroline Badejogbin, Mary Olaoluwa Agunloye, Ojichukwuka Ebere Chijioke-Agu, Makinde Vincent Olubiyi, Success Oluwanifesimi Olugbuyiro, Olaniyi Azeez Soetan, Opeyemi Abel Bamgbose, Tobi Opeyemi Olaleye, Swaran J. S. Flora   +8 more
wiley   +1 more source

Metabolic Shifts Induced by Treatment with Statin Influences Circulating Concentrations of the Stress Hormone, Cortisol, but Has Different Effects on Selected Cytokines, Adipokines and Neuropeptides in Lean and Fat Lines of Young Pigs. [PDF]

Metabolites
Pierzchała-Koziec K, Scanes CG, Zubel-Łojek J, Kucharski M.   +3 more
europepmc   +1 more source

Ultrastructural Analysis of the Saphenous Vein Endothelium in a Patient With Proinflammatory Comorbidities Undergoing Coronary Artery Bypass Grafting

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
The saphenous vein (SV) remains one of the most widely used grafts in coronary artery bypass grafting (CABG), and the integrity of the endothelium—a complex structure susceptible to deleterious effects from proinflammatory comorbidities—is a critical factor for graft patency. A 75‐year‐old patient with hypertension, dyslipidemia, insulin‐dependent Type
Matheus Duarte Pimentel, Heraldo Guedis Lobo Filho, José Glauco Lobo Filho, Sreeja Dattachoudhury   +3 more
wiley   +1 more source