Results 191 to 200 of about 304,614 (388)

The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

Neurogastroenterology &Motility, EarlyView.
Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner, Schneider Linda, Hamza Ebrahim, Leven Patrick, Wehner Sven   +4 more
wiley   +1 more source

Preventive effects of BQ-123, an endothelin ETA receptor antagonist, on cerebral vasospasm following subarachnoid hemorrhage in dogs.

, 1994
Hiroyasu Hirose, Risa Takahashi, Mitsuo Yano, Masaru Nishikibe   +3 more
openalex   +1 more source

Why not consider an endothelin receptor antagonist against SARS-CoV-2? [PDF]

Med Hypotheses, 2020
Javor S, Salsano A.
europepmc   +1 more source

Local regulation of the coronary circulation in health and disease: role of nitric oxide and endothelin [PDF]

, 2016
Coronary artery disease is the leading cause of morbidity and mortality in western countries. Its pathogenesis is unknown, but involves enhanced vasoconstriction, increased interaction of platelets and monocytes with the vessel wall, as well as ...
Lüscher, T. F., Noll, G., Wenzel, R. R.
core  

Inspiratory Muscle Training on Exercise Capacity, Dyspnoea and Health Status in Pulmonary Hypertension: A Randomised Controlled Trial

Respirology, EarlyView.
ABSTRACT Background and Objective To evaluate the effects of a high‐intensity inspiratory muscle training on respiratory muscle strength, exercise capacity, dyspnoea, and health‐related quality of life (HRQL) in patients with pulmonary hypertension (PH). Methods Single‐blinded, randomised controlled trial 35 women with clinically stable PH (subgroups 1
Fabrício Farias da Fontoura, Gabriela Roncato, Gisela Martina Bohns Meyer, Cássia da Luz Goulart, Fernanda Brum Spilimbergo, Gerson Cipriano Junior, Marilia Gabriela Bernadeli, Katya Rigatto, Danilo Cortozi Berton   +8 more
wiley   +1 more source

Macitentan for the treatment of pulmonary arterial hypertension

Vascular Health and Risk Management, 2014
Cyrus A Kholdani,1 Wassim H Fares,2 Terence K Trow2 1Section of Pulmonary, Critical Care and Sleep Medicine, 2Yale Pulmonary Vascular Disease Program, Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale ...
Kholdani CA, Fares WH, Trow TK
doaj  

Integrating computational detection and experimental validation for rapid GFRAL-specific antibody discovery [PDF]

arXiv
The identification and validation of therapeutic antibodies is critical for developing effective treatments for many diseases. We present a computational approach for identifying antibodies targeting GFRAL-specific receptors, receptors implicated in appetite regulation. Using humanized Trianni mice, we conducted a longitudinal study with repeated blood
arxiv  

Altered Expression of Isoforms of Myosin Heavy Chain mRNA in the Failing Rat Heart Is Ameliorated by Chronic Treatment with an Endothelin Receptor Antagonist

, 1998
Satoshi Sakai, Takashi Miyauchi, Tsutomu Kobayashi, Iwao Yamaguchi, Katsutoshi Goto, Yasuro Sugishita   +5 more
openalex   +1 more source

Safety and efficacy of the endothelin receptor antagonist macitentan in pediatric pulmonary hypertension. [PDF]

Cardiovasc Diagn Ther, 2020
Schweintzger S, Koestenberger M, Schlagenhauf A, Grangl G, Burmas A, Kurath-Koller S, Pocivalnik M, Sallmon H, Baumgartner D, Hansmann G, Gamillscheg A.   +10 more
europepmc   +1 more source

Attenuation of ischemic liver injury by a non-selective endothelin receptor antagonist [PDF]

, 1997
Ishizaki, N, Jin, MB, Lee, RG, Starzl, TE, Subbotin, VM, Tanaka, H, Todo, S, Zhang, S, Zhu, Y   +8 more
core   +1 more source