Results 211 to 220 of about 304,614 (388)

Impact of acute caffeine intake on local tolerance to cold before and after total sleep deprivation

Experimental Physiology, EarlyView.
Abstract Total sleep deprivation (TSD) alters local cold tolerance and could thus increase the risk of cold injury. We evaluated the impact of acute caffeine intake, the main countermeasure to TSD‐related deleterious effects, on local cold tolerance before and after TSD.
Baptiste de Lorgeril, Pierre‐Emmanuel Tardo‐Dino, Cyprien Bourrilhon, Michael Quiquempoix, Catherine Drogou, Lise Mateo, Mégane Erblang, Philippe Colin, Pascal Van Beers, Mounir Chennaoui, Danielle Gomez‐Merino, Fabien Sauvet   +11 more
wiley   +1 more source

Cyclic Pentapeptide Endothelin A Receptor Antagonists with Attenuated in Vivo Clearance.

, 1996
Tatsuki Fukami, Kenji Niiyama, Y. Amano, Akihiro Hisaka, Naoko Fujino, Yoshio Sawasaki, M. Ihara, Kinji Ishikawa   +7 more
openalex   +2 more sources

The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A cross-species comparison of its cytochrome P450 induction pattern. [PDF]

Pharmacol Res Perspect, 2020
Treiber A, Delahaye S, Seeland S, Gnerre C.   +3 more
europepmc   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

The Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk, Joost H. N. Schuitemaker, Marijke M. Faas, Alexandra M. Smink   +3 more
wiley   +1 more source

Comparison of Transcriptional Activation by Corticosteroids of Human MR (Ile-180) and Human MR Haplotype (Ile180Val) [PDF]

arXiv
While the classical function of human mineralocorticoid receptor (MR) is to regulate sodium and potassium homeostasis through aldosterone activation of the kidney MR, the MR also is highly expressed in the brain, where the MR is activated by cortisol in response to stress. Here, we report the half-maximal response (EC50) and fold-activation by cortisol,
arxiv  

Organocatalytic Enantioselective Conjugate Addition of Nitromethane to Benzylidene-2-Benzoyl Acetate: Asymmetric Synthesis of ABT - 627, an Endothelin Receptor Antagonist. [PDF]

Front Chem, 2020
Hajra S, Aziz SM, Jana B, Hazra S.
europepmc   +1 more source

Clarifying endothelin type B receptor function [PDF]

, 2006
Pollock, D.M., Schneider, M.P.
core   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Amelioration of glyceril-induced acute renal failure in rats by an endothelin a receptor antagonist (S-0139)

, 1997
Toshikatsu Shimizu, Takayuki Kuroda, Satoshi Hata, Masafumi Fujimoto   +3 more
openalex   +1 more source

Endothelin Receptor Antagonist Prevents Parathyroid Cell Proliferation of Low Calcium Diet-Induced Hyperparathyroidism in Rats [PDF]

, 2001
Y. Kanesaka
openalex   +1 more source