Results 231 to 240 of about 40,821 (327)

Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial‐Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats

Stem Cells International, Volume 2026, Issue 1, 2026.
Erectile dysfunction (ED) is widespread among individuals with high blood pressure and negatively affects quality of life. The effect of stromal vascular fraction (SVF) on hypertension‐related ED remains unexplored. We used a hypertensive rat model to explore the relative efficacy of adipose tissue stromal vascular fraction (tSVF) and cellular SVF ...
Cheng Shao, Yi Sun, Jun Zhao, Chao Ju, Tianli Yang, Jingyu Liu, Liuhua Zhou, Ruipeng Jia, Feng Zhao, Harleen Khatra   +9 more
wiley   +1 more source

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from DAPA‐CKD and FIGARO‐DKD

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 750-753, January 2026.
Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink   +4 more
wiley   +1 more source

Perivascular adipose tissue from female rats fed a high‐fat diet impaired mesenteric artery vasodilation

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract High‐fat diet (HFD) is a cardiovascular risk factor that may disproportionately affect women compared to men. HFD alters perivascular adipose tissue (PVAT), which surrounds arteries and regulates vascular function. This study investigated the sex‐specific effects of HFD on PVAT‐mediated vascular dysfunction. Male and female Sprague‐Dawley rats
Gurneet S. Sangha, Ryan M. Sapp, Callie M. Weber, Donaysia Torbit, Nimisha Rangachar, Anne Barnes, Alisa M. Clyne   +6 more
wiley   +1 more source

[Using nonselective endothelin receptor antagonist in idiopathic pulmonary hypertension].

, 2010
О А Архипова, Архипова Ольга Александровна, Tamila Vital'evna Martynyuk, Мартынюк Тамила Витальевна, V. K. Lazutkina, Лазуткина Валентина Кирилловна, Д М Атауллаханова, Атауллаханова Дильбар Мукумовна   +7 more
openalex   +1 more source

Effects of arginine vasopressin deficiency on cardiac fibrosis in male Wistar rats

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Cardiac fibrosis represents a consequence of hypertensive heart disease and is associated with ventricular dysfunction, arrhythmias, and mortality. Arginine vasopressin (AVP) promotes myofibroblast proliferation and collagen synthesis through V1a receptors.
A. Limón‐Mendoza, J. Alamilla‐Rasso, S. González‐Nuñez, M. Becerra‐Mendez, S. García‐Álvarez, K. Tinajero‐Vidales, M. Tinajero‐Ruelas, A. Quintanar‐Stephano   +7 more
wiley   +1 more source

MACITENTAN: THE EVOLUTION OF THE CLASS ENDOTHELIN RECEPTOR ANTAGONISTS TO IMPROVE EFFICACY AND SAFETY OF PAH TREATMENT

, 2013
T. V. Маrtynuk, С. Н. Наконечников, I. Ye. Chazova   +2 more
openalex   +2 more sources

Beyond vasodilator: anti-apoptotic effect of endothelin receptor antagonist. [PDF]

Korean Circ J, 2014
Chang SA.
europepmc   +1 more source

Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of N-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ET_A Selective Antagonist

, 2002
Natesan Murugesan, Zhengxiang Gu, Steven H. Spergel, M. G. YOUNG, Ping Chen, Arvind Mathur, Leslie Leith, Mark A. Hermsmeier, Eddie C.‐K. Liu, Rongan Zhang, Eileen Bird, Tom Waldron, Anthony M. Marino, Barry Koplowitz, W. Griffith Humphreys, Saeho Chong, Richard A. Morrison, Maria L. Webb, Suzanne Moreland, N. C. Trippodo, Joel C. Barrish   +20 more
openalex   +1 more source

The gastrointestinal endothelin system: receptors, cellular actions, and involvement in gastrointestinal disorders. [PDF]

Prz Gastroenterol
Singh A, Singh R.
europepmc   +1 more source

Endothelin as a Treatment Target in Cardiovascular Diseases: A Recent Step Forward. [PDF]

Rev Cardiovasc Med
Cole A, Kiełbowski K, Dach A, Szulc J, Bakinowska E, Pawlik A.   +5 more
europepmc   +1 more source