Results 231 to 240 of about 304,614 (388)

The Selective Endothelin-A-Receptor Antagonist LU 135.252 Inhibits the Direct Arrhythmogenic Action of Endothelin-1

, 2000
Béla Merkely, Tamás Szab, Lászl Gellér, Orsolya Kiss, Ferenc Horkay, Manfred Raschack, Alexander Juhász‐Nagy   +6 more
openalex   +1 more source

Endothelin‐A receptor antagonist inhibits angiotensin II and noradrenaline in man [PDF]

, 2001
René R. Wenzel, Jens Rüthemann, Heike Bruck, Rainhild Schäfers, Martin C. Michel, Th. Philipp   +5 more
openalex   +1 more source

Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re‐PHIRE

ESC Heart Failure, Volume 12, Issue 3, Page 1956-1964, June 2025.
Abstract Aims Despite receiving guideline‐directed medical heart failure (HF) therapy, patients with pulmonary hypertension associated with left heart disease (PH‐LHD) experience higher mortality and hospitalization rates than the general HF population.
Marcin Ufnal, Kathleen Connolly, Marcus Millegard, Elena Surkova, Marco Guazzi, Diana Bonderman, Justin Ezekowitz, Finn Gustafsson, Michał Ciurzyński, Raquel López Vilella, Tariq Ahmad, Roy Gardner, Pavel Jansa, Sandra van Wijk, Koichiro Kinugawa, Erik Björklund, Zhi‐Cheng Jing, Stephan Rosenkranz   +17 more
wiley   +1 more source

The effect and mechanism of endothelin-1-induced intracellular free calcium in human lung adenocarcinoma cells SPC-A1

Chinese Journal of Lung Cancer, 2008
Background and objective Endothelin-1 (ET-1) is a potent mitogen involved in cell growth in human lung adenocarcinoma cells SPC-A1. The increase in intracellular free calcium ([Ca2+]i) plays a great role in this process.
Juan ZHOU, Weimin ZHANG, Qianjun YE, Gang JIA   +3 more
doaj  

Therapy with the Nonpeptide Endothelin Receptor Antagonist 97-139 in a Murine Model of Congestive Heart Failure. Reduction of Cardiac Mass and Myofiber Hypertrophy.

, 2000
Yukihiro Seta, Tsugiyasu Kanda, T Yokoyama, Masashi Arai, Kenichi Sekiguchi, Tohru Tanaka, Isao Kobayashi, Ryozo Nagai   +7 more
openalex   +2 more sources

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

Journal of the Science of Food and Agriculture, Volume 105, Issue 8, Page 4168-4177, June 2025.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar, Deepika Kaushik, Shubham Shubham, Ashwani Kumar, Vishal Kumar, Emel Oz, Charles Brennan, Maomao Zeng, Charalampos Proestos, Kenan Çadırcı, Muharrem Bayrak, Tahra Elobeid, Sercan Karav, Fatih Oz   +13 more
wiley   +1 more source

Effects of an Endothelin Receptor Antagonist TAK-044 on Myocardial Energy Metabolism in Ischemia/Reperfused Rat Hearts

, 2000
Masaru Iimuro, Masanori Kaneko, Yuji Matsumoto, Yutaka Fujise, Toshifumi Watanabe, Hideharu Hayashi   +5 more
openalex   +1 more source

Effects of the novel selective endothelin ET_A receptor antagonist, SB 234551, on the cardiovascular responses to endotoxaemia in conscious rats [PDF]

, 2001
Sheila M. Gardiner, J E March, P.A. Kemp, T. Bennett   +3 more
openalex   +1 more source

The effect of the endothelin receptor antagonist atrasentan on insulin resistance in phenotypic clusters of patients with type 2 diabetes and chronic kidney disease. [PDF]

Diabetes Obes Metab
Smeijer JD, Gomez MF, Rossing P, Heerspink HJL.   +3 more
europepmc   +1 more source

New Mechanisms and Therapeutic Targets in Systemic Lupus Erythematosus

MedComm, Volume 6, Issue 6, June 2025.
Systemic lupus erythematosus (SLE) is a multiple organ involved autoimmune disorder with heterogeneous clinical manifestations. Despite hallmark features such as elevated type I interferon and the production of numerous autoantibodies, the underlying pathogenic mechanisms remain elusive.
Jingru Tian, Hang Zhou, Wei Li, Xu Yao, Qianjin Lu   +4 more
wiley   +1 more source