Results 131 to 140 of about 36,666 (331)

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

Modulation of rhodopsin gene expression and signaling mechanisms evoked by endothelins in goldfish and murine pigment cell lines

open access: yesBrazilian Journal of Medical and Biological Research, 2010
Endothelins (ETs) and sarafotoxins (SRTXs) belong to a family of vasoconstrictor peptides, which regulate pigment migration and/or production in vertebrate pigment cells.
G.J.D. Lopes   +3 more
doaj  

History of pre‐eclampsia negatively impacts stroke severity postpartum in rats

open access: yesNeuroprotection, EarlyView.
Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf   +4 more
wiley   +1 more source

Efficient Regioselective Iodination of Pyrazole Derivatives Mediated by Cadmium(II) Acetate

open access: yesChemistryOpen, EarlyView.
The iodination reactions of both N, C alkyl‐, propargylic substituted and unsubstituted pyrazole derivatives initiated by cadmium (II) acetate were performed. It was revealed that the C‐4 position of the pyrazole ring was more nucleophilic. The nucleophilicity of the pyrazole ring significantly increased due to the influence of alkyl groups and ...
Nina G. Hobosyan   +8 more
wiley   +1 more source

Hemodynamic and inotropic effects of endothelin-1 in vivo [PDF]

open access: yes, 1994
Endothelin-1 (ET-1) is known to have strong vasoactive properties. Contradictory results have been reported with regard to its inotropic effects. This study examined the dose-dependent (500, 1000, 2500, 5000 and 10,000 ng ET-1/kg vs.
Beyer, M. E.   +3 more
core  

Pharmacotherapy for Cirrhosis in Japan

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

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