Results 141 to 150 of about 4,400 (309)

Structural insights into endothelin receptor signalling. [PDF]

J Biochem, 2023
Shihoya W, Sano FK, Nureki O.
europepmc   +1 more source

Differential glial and vascular expression of endothelins and their receptors in rat brain after neurotrauma

, 2000
We characterized the time-course, intensity of expression and cellular origin of components of the endothelin (ET) system in the rat brain after a standardized neurotrauma (cryogenic lesion of the parietal cortex).
Knerlich, F., Schilling, L., Ehrenreich, Hannelore, Kamrowski-Kruck, Heike, Hahn, A., Siren, A. L.   +5 more
core   +1 more source

Menopause and vascular endothelial health: Is it all about the oestrogen?

Experimental Physiology, EarlyView.
Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols, Allyson I. Schwab, Lyndsey E. DuBose, Kerrie L. Moreau, Megan M. Wenner   +4 more
wiley   +1 more source

Endothelin-3 is epigenetically silenced in endometrioid endometrial cancer. [PDF]

J Cancer Res Clin Oncol, 2023
Zmarzły N, Januszyk S, Mieszczański P, Morawiec E, Buda P, Dziobek K, Opławski M, Boroń D.   +7 more
europepmc   +1 more source

Antidipsogenic actions of endothelins are exerted via the endothelin-A receptor in the brain

, 1993
The receptor subtype mediating the antidipsogenic effects of the endothelins (ETs) was determined in conscious, unrestrained, normally hydrated rats.
T. C. Murphy, W. K. Samson
core   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

Experimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves, Rheure Alves‐Lopes, Augusto C. Montezano, Rhian M. Touyz   +3 more
wiley   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Gene expression of endothelin receptors in replaced rheumatic mitral stenotic valves Expressão gênica de receptores de endotelina em valvas mitrais reumáticas estenóticas substituídas

Brazilian Journal of Cardiovascular Surgery, 2012
OBJECTIVES: Rheumatic fever is a highly prevalent disease in Brazil, and it poses a major public health problem. It is the leading cause of acquired heart disease in childhood and adolescence.
Sydney Correia Leão, Fernanda Maria Silveira Souto, Ricardo Vieira da Costa, Thaisa de Fatima Almeida Rocha, Yolanda Galindo Pacheco, Tania Maria de Andrade Rodrigues   +5 more
doaj  

The Tetraspanin Tspan8 Associates with Endothelin Converting Enzyme ECE1 and Regulates Its Activity. [PDF]

Cancers (Basel), 2023
Zhu Y, Saint-Pol J, Nguyen V, Rubinstein E, Boucheix C, Greco C.   +5 more
europepmc   +1 more source