Endogenous modulators in lung cancer. [PDF]
Patel N, Patel V, Surani S.
europepmc +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
The gastrointestinal endothelin system: receptors, cellular actions, and involvement in gastrointestinal disorders. [PDF]
Singh A, Singh R.
europepmc +1 more source
Can improving your aerobic fitness negate the immediate vascular consequences of prolonged sitting?
Experimental Physiology, EarlyView.
Molly K. Courish, Myles W. O'Brien
wiley +1 more source
Natural History of Chronic Kidney Disease in Sickle Cell Disease
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley +1 more source
Role of nitric oxide, prostaglandins, thromboxanes and endothelins in lung cancer: An overview. [PDF]
Demirel S, Sinag IN.
europepmc +1 more source
Endothelins: functional and autoradiographic studies in guinea pig trachea
peer reviewedThe presence of binding sites for [125I]endothelin-1 and the contractile activities of endothelins (ETs) and sarafotoxin S6b and the endothelin fragment ET(16-21) were investigated in guinea pig trachea.
Miller, R. C. +4 more
core
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
Endothelin-2 and Its Association with Uric Acid Levels and Systemic Inflammation: Relevance to Chronic Kidney Disease Progression. [PDF]
Blazhev AB +5 more
europepmc +1 more source
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du +7 more
wiley +1 more source

