, 1998 We studied rats with a hemi-parkinsonian model created by lesions of mesostriatal dopaminergic neurons. Correlation between the extent of lesions and intensity of forced rotation movements (apomorphine (APO)-induced rotations, i.e., exercise) was ...
Bazilyuk O. V. +7 more
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Understanding pre‐eclampsia and fetal growth restriction at high altitude: A narrative review
International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 62-69, July 2026.Abstract Pre‐eclampsia (PE) and fetal growth restriction (FGR) are among the leading causes of maternal and perinatal morbidity and mortality worldwide. Both conditions are more frequent and severe at high altitudes due to physiological changes in oxygen availability and vascular adaptation.
Víctor S. Rangel +6 more
wiley +1 more source
Endothelin antagonists for hypertension: has their time finally arrived? [PDF]
Clin Sci (Lond)Schiffrin EL.
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Some aspects of trypsin's involvement in the regulation of physiological functions. [PDF]
Front Mol BiosciKuzmina IV, Tolpygo SM, Vertiprakhov VG.
europepmc +1 more source
The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song +6 more
wiley +1 more source
Interplay Between the Mineralocorticoid System, Inflammation, Hypertension, and Kidney Disease. [PDF]
Kidney360Fields E, Schiffrin EL.
europepmc +1 more source
Protein and Peptide Inhibitors of Mineralization: A Systematic Review of In Vitro Studies
Journal of Peptide Science, Volume 32, Issue 7, July 2026.In vitro evidence from crystallization assays demonstrates that peptides inhibit mineral nucleation and crystal growth through sequence‐dependent interactions (acidic residues and phosphorylation) with mineral surfaces. In cell cultures, these molecules reduce calcium deposition and ALP activity and modulate the expression of biomineralization‐related ...
Alberto Mimila‐Cortes +7 more
wiley +1 more source
Endothelin in renal disease: role of endothelin antagonists [PDF]
Nephrology Dialysis Transplantation, 1995 T F, Lüscher, R R, Wenzel
openaire +2 more sources
The metabolism of big endothelin-1 axis and lipids affects carotid atherosclerotic plaque stability - the possible opposite effects of treatment with statins and aspirin. [PDF]
Pharmacol RepPłoński A +8 more
europepmc +1 more source