Results 71 to 80 of about 36,666 (331)
Diabetic foot disease and oedema [PDF]
, 2013 Diabetic foot ulcers (DFUs) are common and disabling, giving rise to significant morbidity and mortality as well as worldwide socioeconomic problems. Despite treatment, DFUs readily become chronic wounds and may lead to major lower limb amputations.
Ho, TK, Leigh, RD, Tsui, J
core +1 more source
Cancer Communications, EarlyView.Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu +12 more
wiley +1 more source
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data
Molecular Systems Biology, 2019 Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available ...
Alexander Schäfer +8 more
doaj +1 more source
Retinal and choroidal angiogenesis: a review of new targets
International Journal of Retina and Vitreous, 2017 Retinal and choroidal neovascularization are a major cause of significant visual impairment, worldwide. Understanding the various factors involved in the accompanying physiopathology is vital for development of novel treatments, and most important, for ...
Thiago Cabral +6 more
doaj +1 more source
Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review
Chronic Diseases and Translational Medicine, EarlyView.PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi +7 more
wiley +1 more source
The correlation of endothelin-1 and dyslipidemia in migraineurs
Chinese Journal of Contemporary Neurology and Neurosurgery, 2013 Objective To detect the levels of serum lipid and endothelin-1 (ET-1) in acute period migraine, and to observe the correlation between them. Methods The serum lipid level in healthy control group (N = 42) and migraine group (N = 95) was detected by ...
Zhong-ju ZHANG, Li YANG
doaj
Rescue with an anti-inflammatory peptide of chickens infected H5N1 avian flu [PDF]
, 2009 Chickens suffering from avian flu caused by H5N1 influenza virus are destined to die within 2 days due to a systemic inflammatory response. Since HVJ infection (1,2) and influenza virus infection (3,4) cause infected cells to activate homologous serum ...
Alan A. Okada +7 more
core +1 more source
Assessing candidate DLX‐regulated genes in the first pharyngeal arch of chick embryos
Developmental Dynamics, EarlyView.Abstract Background Insights into the development and evolution of asymmetrical jaws will require an understanding of the gene regulatory networks that underpin the differential morphogenesis of the maxillary and mandibular domains of the first pharyngeal arch in a variety of gnathostomes.
Afshan Sohail +2 more
wiley +1 more source
Regulation of Cerebral Blood Flow
International Journal of Vascular Medicine, 2011 The control of cerebral blood flow is complex, and only beginning to be elucidated. Studies have identified three key regulatory paradigms. The first is cerebral pressure autoregulation, which maintains a constant flow in the face of changing cerebral ...
Eric C. Peterson +2 more
doaj +1 more source