Results 91 to 100 of about 4,400 (309)

Keratinocytes regulate the function of melanocytes

open access: yesDermatologica Sinica, 2014
Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
doaj   +1 more source

Pulmonary vasodilation in acute pulmonary embolism – a systematic review

open access: yesPulmonary Circulation, 2020
Acute pulmonary embolism is the third most common cause of cardiovascular death. Pulmonary embolism increases right ventricular afterload, which causes right ventricular failure, circulatory collapse and death.
Mads Dam Lyhne   +3 more
doaj   +1 more source

Endothelins 1 and 3 and big endothelin-1 contract isolated human placental veins

open access: yes, 1993
Experiments were designed to investigate the reactivity of vascular smooth muscle to endothelins (ETs) in veins taken from human placentas immediately after delivery.
Vanhoutte, PM   +3 more
core   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

open access: yesInterdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong   +15 more
wiley   +1 more source

Tear fluid as a source of biomarkers for glaucoma

open access: yesРоссийский офтальмологический журнал
Review presents the analysis of literature data about metabolic changes in tear fluid (TF) of patients with glaucoma. Data for mass-spectrometry of TF proteome, cytokine profile, neurotrophic factors, proteinases and their inhibitors, extracellular ...
N. B. Chesnokova   +2 more
doaj   +1 more source

Endothelin-1 Induced Vascular Smooth Muscle Cell Proliferation is Mediated by Cytochrome P-450 Arachidonic Acid Metabolites

open access: yesBiomolecules & Biomedicine, 2010
Endothelins (ETs) are a family of three peptides (ET-1, ET-2, ET-3) that are implicated in the physiological control of vascular smooth muscle cell (VSMC) and myocardial contractility and growth.
Farid Ljuca, Gorazd Drevenšek
doaj   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Endothelins and their receptors in retina after excitotoxic injury.

open access: yes, 2016
(A) Schematic tree depicting orthologs and paralogs of the endothelin receptors (EDNRs) in Aves and Mammalia. EDNR2B has only been found in non-mammalian species. The tree is based on Ensembl Gene tree ID: ENSGT00760000119177.
Mohammad Harun-Or-Rashid (115267)   +3 more
core   +1 more source

Hell's Itch: A Self‐Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Hell's itch is a severely distressing dermatological condition characterized by the onset of incessant itching and intolerable pain 2–3 days post‐sunburn. It is underdiagnosed and underreported, and no definitive management framework has yet been developed.
Kai Peter Moors, Willem I. Visser
wiley   +1 more source

The delays in intestinal motility and neutrophil infiltration following burn injury in rats involve endogenous endothelins

open access: yes, 2000
This study was carried out to investigate the role of endogenous endothelins in intestinal motility following bum injury by using a nonselective endothelin-1 (ET-1) antagonist and to evaluate the ET-1-mediated reactive oxygen metabolite formation and ...
YEGEN, ŞEVKET CUMHUR, YEGEN, BERRAK
core   +2 more sources

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