Results 71 to 80 of about 4,400 (309)

Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data

open access: yesMolecular Systems Biology, 2019
Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available ...
Alexander Schäfer   +8 more
doaj   +1 more source

Endotelina-1 induz comportamento de coçar quando administrada no dorso de camundongos [PDF]

open access: yes, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.
Trentin, Patrícia Gonçalves
core  

Apoptosis, ANUP, Chromogranin A, PGP 9.5, Endothelins and VEGF in Acquired Heart Diseases : Review of Literature [PDF]

open access: yes, 2015
According to the Centre for Disease Prevention and Control of Latvia data, in 2014 16076 latvians died from cardiovascular diseases and it is 57,03% of all deaths.
Pilmane, Māra   +2 more
core   +1 more source

SPARCL1 and NT‐proBNP as biomarkers of right ventricular‐to‐pulmonary artery uncoupling in pulmonary hypertension

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1416-1426, April 2025.
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr   +15 more
wiley   +1 more source

The correlation of endothelin-1 and dyslipidemia in migraineurs

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2013
Objective To detect the levels of serum lipid and endothelin-1 (ET-1) in acute period migraine, and to observe the correlation between them. Methods The serum lipid level in healthy control group (N = 42) and migraine group (N = 95) was detected by ...
Zhong-ju ZHANG, Li YANG
doaj  

Regulation of Cerebral Blood Flow

open access: yesInternational Journal of Vascular Medicine, 2011
The control of cerebral blood flow is complex, and only beginning to be elucidated. Studies have identified three key regulatory paradigms. The first is cerebral pressure autoregulation, which maintains a constant flow in the face of changing cerebral ...
Eric C. Peterson   +2 more
doaj   +1 more source

Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice. [PDF]

open access: yesPLoS ONE, 2014
Brain edema is a potentially fatal pathological condition that often occurs in stroke and head trauma. Following brain insults, endothelins (ETs) are increased and promote several pathophysiological responses.
Shotaro Michinaga   +7 more
doaj   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

open access: yesFood Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima   +4 more
wiley   +1 more source

Endothelin XIII

open access: yesLife Sciences, 2014
Twenty-five years ago, a groundbreaking paper from Tsukuba University in Japan was published, identifying the sequence of the endothelin gene and peptide (Nature 332, 411-415, 1988). This work opened the way for the discovery of the endothelin receptors and the development of orally active endothelin receptor antagonists (ERAs). Today, ERAs are part of
Emoto, N   +4 more
openaire   +4 more sources

Endothelins inhibit cyclic-AMP induced renin gene expression in cultured mouse juxtaglomerular cells

open access: yes, 1996
Endothelins inhibit cyclic-AMP induced renin gene expression in cultured mouse juxtaglomerular cells. We have recently described that endothelins-1 to -3 equipotently inhibit cAMP stimulated renin secretion from cultured mouse juxtaglomerular cells by a ...
Kurtz, Armin   +3 more
core   +1 more source

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