Results 71 to 80 of about 4,400 (309)
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data
Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available ...
Alexander Schäfer +8 more
doaj +1 more source
Endotelina-1 induz comportamento de coçar quando administrada no dorso de camundongos [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.
Trentin, Patrícia Gonçalves
core
Apoptosis, ANUP, Chromogranin A, PGP 9.5, Endothelins and VEGF in Acquired Heart Diseases : Review of Literature [PDF]
According to the Centre for Disease Prevention and Control of Latvia data, in 2014 16076 latvians died from cardiovascular diseases and it is 57,03% of all deaths.
Pilmane, Māra +2 more
core +1 more source
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr +15 more
wiley +1 more source
The correlation of endothelin-1 and dyslipidemia in migraineurs
Objective To detect the levels of serum lipid and endothelin-1 (ET-1) in acute period migraine, and to observe the correlation between them. Methods The serum lipid level in healthy control group (N = 42) and migraine group (N = 95) was detected by ...
Zhong-ju ZHANG, Li YANG
doaj
Regulation of Cerebral Blood Flow
The control of cerebral blood flow is complex, and only beginning to be elucidated. Studies have identified three key regulatory paradigms. The first is cerebral pressure autoregulation, which maintains a constant flow in the face of changing cerebral ...
Eric C. Peterson +2 more
doaj +1 more source
Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice. [PDF]
Brain edema is a potentially fatal pathological condition that often occurs in stroke and head trauma. Following brain insults, endothelins (ETs) are increased and promote several pathophysiological responses.
Shotaro Michinaga +7 more
doaj +1 more source
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
Twenty-five years ago, a groundbreaking paper from Tsukuba University in Japan was published, identifying the sequence of the endothelin gene and peptide (Nature 332, 411-415, 1988). This work opened the way for the discovery of the endothelin receptors and the development of orally active endothelin receptor antagonists (ERAs). Today, ERAs are part of
Emoto, N +4 more
openaire +4 more sources
Endothelins inhibit cyclic-AMP induced renin gene expression in cultured mouse juxtaglomerular cells
Endothelins inhibit cyclic-AMP induced renin gene expression in cultured mouse juxtaglomerular cells. We have recently described that endothelins-1 to -3 equipotently inhibit cAMP stimulated renin secretion from cultured mouse juxtaglomerular cells by a ...
Kurtz, Armin +3 more
core +1 more source

