NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy. [PDF]
Xie L +10 more
europepmc +1 more source
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source
ABSTRACT Background and Aims Herpes simplex virus (HSV) infection is common worldwide, but hepatic involvement is rare. HSV hepatitis is an uncommon yet frequently catastrophic cause of acute hepatitis and acute liver failure (ALF), accounting for < 1% of ALF cases while carrying very high mortality when diagnosis and antiviral therapy are delayed ...
Mario U. Mondelli +5 more
wiley +1 more source
Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs. [PDF]
Suk H, Kim M, Kim D, Kang S, Seo K.
europepmc +1 more source
ZEB1 Modifies VE‐Cadherin Signaling in Lymphatic Endothelial Cells
ABSTRACT Objective Zinc finger E‐box‐binding homeobox 1 (ZEB1) is a transcription factor primarily known for its regulatory roles in epithelial‐to‐mesenchymal transition (EMT) and cell fate determination. Recent studies suggest that endothelial ZEB1 signaling promotes blood vessel growth and reduces junctional integrity, although the underlying ...
Nada S. Ahmed +17 more
wiley +1 more source
Recent advances in corneal specular microscopy image analysis through artificial intelligence. [PDF]
Marrugo AG +5 more
europepmc +1 more source
Evaluation of the Ovine Corneal Endothelium Using a Human Eye Bank Specular Microscope
ABSTRACT This study aimed to evaluate the feasibility of visualizing and quantitatively analyzing the corneal endothelium of sheep using a specular microscope designed for a human eye bank. Twenty‐four healthy corneas from 12 one‐year‐old male sheep (Ovis aries) were examined.
Tanise Carboni da Silva +6 more
wiley +1 more source
Linking layered corneal compactness to macroscopic biomechanics: <i>in vivo</i> assessment via integrated densitometry and dynamic deformation analysis. [PDF]
Deng F +6 more
europepmc +1 more source
ABSTRACT Objective To identify commonly presented dog breeds and potentially heritable ophthalmic diseases encountered by veterinarians practicing ophthalmology in Japan. Methods A survey was distributed through the Japanese Society of Comparative and Veterinary Ophthalmology.
Victoria Caballero +8 more
wiley +1 more source
Putative Self-Organizing Human Corneal Organoids Recapitulate Human Corneal Architecture and Cellular Diversity. [PDF]
Blenkinsop TA, Eriksen AZ.
europepmc +1 more source

