Results 121 to 130 of about 20,485 (245)

Limited Efficacy of Autologous Mesenchymal Stromal Cell Injections in Immunomodulatory‐Dependent Dogs With Aqueous Deficient Dry Eye Disease

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective Aqueous deficient dry eye disease (ADDE) results from a quantitative reduction in aqueous tears. We sought to determine the clinical effect of autologous mesenchymal stromal cell (MSC) injections into the region of the lacrimal gland and the gland of the third eyelid in immunomodulatory‐dependent ADDE‐affected dogs. Methods Dogs (n = 
Brian C. Leonard, Shin Ae Park, Sun Young Kim, Kei Hayashi, Sara M. Thomasy, Vanessa Rozo, Monica J. Motta, Dori L. Borjesson, Christopher J. Murphy, Kathryn L. Good   +9 more
wiley   +1 more source

Nephronectin Promotes Migration of the Periocular Mesenchyme via EGFR Signaling. [PDF]

Invest Ophthalmol Vis Sci
Garis MR, Chiu ES, Lwigale PY.
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, Volume 13, Issue 43, 3 August 2026.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Generation of a Novel Col8a2^P2A-CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation. [PDF]

Genesis
Yuan Y, Holt J, Lorry S, Wang YC, Hu YC, Ma Z, Kaufman A, Kao W, Ogando DG, Liu CY.   +9 more
europepmc   +1 more source

The Interstitial Fluid Compartment: Still Unrecognized or Biophysically Well Described?

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ABSTRACT The proposal of a “new third bodily system for circulation of fluid” has been recently put forward. The present article sheds light on all available physiological knowledge concerning exactly this same space, defined as “interstitial compartment” as originally hypothesized by Ernest Starling about 130 years ago. We provide here a brief updated
Daniela Negrini, Giuseppe Miserocchi
wiley   +1 more source

Long-term observation of the endothelium morphology and corneal thickness in myopic adolescents treated with orthokeratology: a 10-year retrospective study. [PDF]

Int J Ophthalmol
Zhao LQ, Wang ZX, Li Y, Wang BY, Du B, Beeman J, Wei RH, Liu L.   +7 more
europepmc   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Effect of intravitreal injection of dexamethasone implant on the corneal morphology of young adults with central retinal vein occlusion. [PDF]

Int J Ophthalmol
Niu TT, Xin WJ.
europepmc   +1 more source

A Lightweight and Erudite Automated BiLSTM‐Based Multi‐Cycle GAN for Retinal Blood Vessel and Optic Disc Segmentation in Fundus Images

Engineering Reports, Volume 8, Issue 8, August 2026.
This graphical abstract presents a lightweight and automated BiLSTM‐based Multi‐Cycle GAN framework for retinal blood vessel and optic disc segmentation in fundus images. Initially, fundus images undergo preprocessing, including green channel extraction, denoising, resizing, and dataset splitting.
Rasmita Kumari Mohanty, Amaravarapu Pramod Kumar, Yuvaraju Macha, Agraharam Siva Kumar, J. Srinivas, G. Shyama Chandra Prasad, Rajesh Kumar Verma, Shashi Kant   +7 more
wiley   +1 more source

NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Xie L, Chen M, Wu J, Li Z, Guo R, Yu H, Li X, Wang Q, Liu F, Wang J, Wang L.   +10 more
europepmc   +1 more source