Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond +6 more
wiley +1 more source
Anterior Chamber Depth and the Long-Term Safety of Implantable Collamer Lens Surgery: A Case for Re-Evaluating Age-Stratified Indication Criteria. [PDF]
Watanabe K.
europepmc +1 more source
Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery
Stromal surface after extraction of the lamella cut with the studied frugal picosecond laser source. ABSTRACT Femtosecond lasers have long been the gold standard for corneal laser‐assisted surgery, but their high cost limits widespread use. This study challenges their supremacy by investigating a cost‐effective alternative: a frugal all‐fiber ...
Maxime Quirke +9 more
wiley +1 more source
The cornea-trigeminal axis: potassium channels as master regulators of ocular surface homeostasis and sensory transduction. [PDF]
Zhang J +7 more
europepmc +1 more source
ABSTRACT Objectives This study aimed to assess the clinical and histopathological effects of maximal available and supramaximal energy exposure in direct selective laser trabeculoplasty (DSLT®) on target and nontarget ocular tissues compared with selective laser trabeculoplasty (SLT) and sham treatments.
Liat Mendel Veig +4 more
wiley +1 more source
The groove and peel technique of manual deep anterior lamellar keratoplasty. [PDF]
Swarup R, Gujar P.
europepmc +1 more source
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li +6 more
wiley +1 more source
Stability selection machine learning identifies biomechanical markers for subclinical idiopathic corneal endothelial abnormalities. [PDF]
Feng C, Chi M, Gu S, Hong J.
europepmc +1 more source
Development of neural crest cells: and contribution to corneal endothelium
Neural crest cells are an early embryonic cell population characterised by their multipotency and high migratory capacity. In addition to contributing to various facial and bodily tissues, including bone and cartilage, neural crest cells play a key role ...
Karsila, Kerttu
core
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source

