Results 171 to 180 of about 161,906 (230)

Netarsudil-Induced Honeycomb Keratopathy in an Eye With Iridocorneal Endothelial Syndrome. [PDF]

Case Rep Ophthalmol Med
Ferguson AN, Bojikian KD, Nguyen MT.
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Impact of COVID-19 on corneal endothelial density and morphology: a cross-sectional study in convalescent patients. [PDF]

Front Med (Lausanne)
Zhang L, Shi W, Guo X, Lv R, Guan H, Zheng F, Gao Y.   +6 more
europepmc   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

MedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song, Epiphane K. Silli, Yazhen Xu, Huixia Lv, Ruoxian Song   +4 more
wiley   +1 more source

Acute Bilateral Corneal Oedema Following Suspected Toxic Endothelial Insult: An Intriguing Case Report. [PDF]

Cureus
Upadhyay P, Rai S, Shrivastava N.
europepmc   +1 more source

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

Corneal Endothelial Safety and Intraocular Pressure Outcomes of MicroPulse Laser Trabeculoplasty in Treatment-Naïve Glaucoma: A Six-Month Retrospective Study. [PDF]

Life (Basel)
Somuncu AM, Uysal AT.
europepmc   +1 more source

FGF21/sirtuin 1 axis mediates the cardioprotective effects of high‐intensity interval training against doxorubicin‐induced cardiotoxicity by reducing inflammatory and oxidative stress

Experimental Physiology, Volume 111, Issue 10, Page 4409-4420, 1 October 2026.
Abstract Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent, but its clinical use is limited by cumulative cardiotoxicity. Exercise, particularly high‐intensity interval training (HIIT), has emerged as an effective non‐pharmacological strategy to counteract chemotherapy‐induced cardiac injury.
Mahdiyeh Farahani, Abbas Ali Gaeini, Alireza Ghardashi Afousi, Mahboobeh Borjian Fard   +3 more
wiley   +1 more source

Effect of chronic high‐altitude hypoxia on retinal vascular phenotype, choroidal and retinal vasoreactivity in Peruvian highlanders

Experimental Physiology, Volume 111, Issue 10, Page 4814-4826, 1 October 2026.
Abstract High‐altitude chronic hypoxia can induce excessive erythrocytosis (EE, defined as a haemoglobin concentration of ≥21 g/dL in men), leading to hyperviscosity and promoting endothelial dysfunction. We aimed to assess whether EE affects the retinal vascular phenotype and the ophthalmological vascular response to CO2.
Aymeric Paillisser, Julien Vincent Brugniaux, Florence Berquet, Jeremy De Abreu, Stephen Hogg, Emanuele Trucco, Martial Geiser, Tom Macgillivray, Aurélien Pichon, Paul Robach, Benoit Champigneulle, Samuel Verges, Christophe Chiquet   +12 more
wiley   +1 more source

Correlation Between Endothelial Morphology, Ocular Biometric Parameters, and Systemic Comorbidities in a Large Caucasian Cohort. [PDF]

J Clin Med
Martinez-de-la-Casa M, Matilla M, Garcia-Bella J, Morales Fernandez L, Garcia-Feijoo J, Martínez-de-la-Casa JM, Burgos-Blasco B.   +6 more
europepmc   +1 more source