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Ionic channels in corneal endothelium

American Journal of Physiology-Cell Physiology, 1996
Single-channel patch-clamp techniques as well as standard and perforated-patch whole cell voltage-clamp techniques have been applied to the study of ionic channels in the corneal endothelium of several species. These studies have revealed two major K+ currents.
J L, Rae, M A, Watsky
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Vital Staining of Corneal Endothelium

Cornea, 1985
The efficacy and applicability of dual vital staining of human and porcine corneal endothelium with trypan blue and alizarin red S stains was investigated. Exposure of endothelial cells to different concentrations of these two dyes for varying periods of time revealed that 0.3% solution of trypan blue for 1 minute followed by 0.2% solution of alizarin ...
G, Singh   +5 more
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Corneal endothelium and growth factors

Survey of Ophthalmology, 1996
Human corneal endothelium is characterized by a low regenerative capacity, mainly because of a low mitotic activity, and therefore complete regeneration of the endothelial layer after injury is precluded. A decrease in endothelial cell density and an abnormal cell mosaic, which may occur after many conditions, can compromise the integrity of the ...
V P, Hoppenreijs   +3 more
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Corneal Endothelium and Phacoemulsification

Cornea, 2016
Phacoemulsification has become the most commonly used procedure in cataract surgery owing to the development of new devices and surgical techniques; however, corneal endothelial damage still represents a serious complication. Although several factors are known to cause corneal endothelial damage, effects of irrigating pressure and temperature rise in ...
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Ultraviolet-B Damages Corneal Endothelium

Optometry and Vision Science, 1984
Direct in vivo observation of acute ultraviolet (UV)-induced corneal endothelial damage is not possible due to the more severe damage produced in the epithelium. In order to quantify damage and evaluate endothelial recovery an indirect method was used.
A P, Cullen   +3 more
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Regeneration of the Corneal Endothelium

Current Eye Research, 2019
Penetrating keratoplasty was the only therapeutic choice for the treatment of corneal endothelial decompensation until the introduction of evolutional endothelial keratoplasties, namely Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK).
Naoki Okumura, Noriko Koizumi
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Corneal Endothelium in Herpetic Keratouveitis

Archives of Ophthalmology, 1983
The corneal endothelium underwent changes in 15 patients with unilateral herpetic keratouveitis. Study with both noncontact and wide-field specular microscopes showed that six patients had mild and nine patients severe keratouveitis. Transient endothelial changes indicating endotheliitis were observed in all eyes affected by severe keratouveitis.
A, Vannas, R, Ahonen, J, Mäkitie
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Ionic transport across corneal endothelium

Acta Ophthalmologica, 1985
Abstract. The active potential difference across bovine corneal endothelium was measured in vitro at different temperatures, pH, osmolality and salt compositions. The measurements were made using either identical or different solutions on each side of the membrane.
A, Lyslo   +3 more
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Morphogenesis of rabbit corneal endothelium

Current Eye Research, 1988
We studied ultrastructurally the development of rabbit corneal endothelium from the 13th day of gestation to 3 days after birth. Precursor corneal endothelial cells, stromal cells, and a vascular network migrate in close association with each other between the developing corneal and lens epithelia.
C, Cintron, H I, Covington, C L, Kublin
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Corneal endothelium after refractive surgery

Journal of Cataract and Refractive Surgery, 2011
The endothelium is vital to the health and optical clarity of the human cornea. The safety of procedures to correct refractive errors depends on preservation of an intact corneal endothelium. Disease states and genetic and environmental factors affect the corneal endothelium; an unstable corneal endothelium can impact the success of refractive surgery.
Maria A, Woodward, Henry F, Edelhauser
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