Results 81 to 90 of about 36,948 (267)
Next generation tyrosine-mutant AAV8 shows high mouse corneal endothelial transduction in vivo [abstract] [PDF]
, 2010 Purpose: Recently, point mutations in surface-exposed tyrosine residues have been shown to increase AAV transduction significantly. We examined the efficacy of conventional AAV8 and next generation tyrosine-mutant AAV8 vectors to deliver genes into ...
Tovey, Jonathan
core
Mesothelial cells: A cellular surrogate for tissue engineering of corneal endothelium [PDF]
, 2015 [Purpose]: To evaluate whether mouse adipose tissue mesothelial cells (ATMCs) share morphologic and biochemical characteristics with mouse corneal endothelial cells (CECs) and to evaluate their capacity to adhere to the decellularized basal membrane of ...
Alió, Jorge +6 more
core +1 more source
Uncovering the role of genetic polymorphisms in cervical insufficiency
International Journal of Gynecology &Obstetrics, EarlyView.Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi +3 more
wiley +1 more source
Cells, 2019 The corneal endothelium regulates corneal hydration to maintain the transparency of cornea. Lacking regenerative capacity, corneal endothelial cell loss due to aging and diseases can lead to corneal edema and vision loss.
Gary Hin-Fai Yam +8 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui +12 more
wiley +1 more source
Tissue engineered corneal endothelium transplantation in an ex vivo human cornea organ culture model
Scientific ReportsTransplantation of corneal tissue is the standard treatment for irreversible corneal endothelium decompensation by replacing the malfunctioning corneal endothelial cells and Descemet’s membrane.
Meng-Chen Tsai +2 more
doaj +1 more source
Effects of intracameral brilliant blue on the corneal endothelium of swine: in vitro study
Pesquisa Veterinária Brasileira: The aim was to investigate the ultrastructural changes in the corneal endothelium of pigs induced by intracameral 0.05% brilliant blue. Twenty swine corneas were separated into two groups, the right eye bulbs (control group) and the left eye bulbs ...
Mariana Terzariol +5 more
doaj +1 more source
Analysis of best corrected visual acuity following corneal refractive surgery comparing low and standard predicted postoperative keratometry [PDF]
, 2018 BACKGROUND: It is a commonly held view in the ophthalmologic community that eyes with sufficiently low calculated postoperative corneal keratometry, less than 35 diopters, should not undergo corrective refractive laser surgery (CRLS) due to the increased
Drake, Ryan Carpenter
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao +7 more
wiley +1 more source
Efeito da posição do bisel da caneta de facoemulsificação no endotélio corneano [PDF]
, 2010 Purpose: To compare the extent of corneal endothelial (CE) cell loss changes in two groups of eyes submitted to phacoemulsification, with the conventional bevel-up tip position in one eye and with the bevel-down tip position in the fellow eye.
COELHO, Roberto Pinto +3 more
core +2 more sources