Results 131 to 140 of about 266,603 (335)
Advanced Healthcare Materials, EarlyView.NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham +16 more
wiley +1 more source
Entrainment of Lymphatic Contraction to Oscillatory Flow [PDF]
arXiv, 2018 Lymphedema, a disfiguring condition characterized by the asymmetrical swelling of the limbs, is suspected to be caused by dysfunctions in the lymphatic system. Lymphangions, the spontaneously contracting units of the lymphatic system, are sensitive to luminal wall shear stress. In this study, the response of the lymphangions to dynamically varying wall
arxiv
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
A one-dimensional mathematical model of collecting lymphatics coupled with an electro-fluid-mechanical contraction model and valve dynamics [PDF]
arXiv, 2017 We propose a one-dimensional model for collecting lymphatics coupled with a novel Electro-Fluid-Mechanical Contraction (EFMC) model for dynamical contractions, based on a modified FitzHugh-Nagumo model for action potentials. The one-dimensional model for a compliant lymphatic vessel is a set of hyperbolic Partial Differential Equations (PDEs). The EFMC
arxiv
eLife, 2017 The lymphatic system controls fluid homeostasis and the clearance of macromolecules from interstitial compartments. In mammals brain lymphatics were only recently discovered, with significant implications for physiology and disease. We examined zebrafish
Max van Lessen +5 more
doaj +1 more source
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]
, 2020 Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C +4 more
core +1 more source
Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche
Advanced Healthcare Materials, EarlyView.Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson +3 more
wiley +1 more source
Journal of Acupuncture & Meridian Studies, 2019 It is known that the primo vascular system (PVS) includes the primo nodes and vessels. However, the relevant genes in the PVS system for both pathologic and physiologic condition are poorly understood. Here, we first examined the gene expression in primo
Jun-Young Shin +7 more
doaj
A comparative study of adhesion of melanoma and breast cancer cells to blood and lymphatic endothelium [PDF]
, 2012 Background: Lymphovascular invasion (LVI) is an important step in the metastatic cascade; tumor cell migration and adhesion to blood and lymphatic vessels is followed by invasion through the vessel wall and subsequent systemic spread.
Hidalgo K +11 more
core +2 more sources
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source