A synergistic multimodality treatment approach to address the key drivers of wound chronicity. [PDF]
Lohr JM +6 more
europepmc +1 more source
ABSTRACT This study elucidates the mechanism by which GLIS Family Zinc Finger 2 (GLIS2) promotes epithelial‐mesenchymal transition (EMT) in gastric cancer through biglycan (BGN) activation and Wnt/β‐catenin stimulation. By analyzing 18 pairs of GC tissues and establishing in vitro models (combining GLIS2 knockdown/BGN overexpression with Wnt pathway ...
Juan Yan, Ya‐Peng Deng
wiley +1 more source
Preoperative Imaging Assessment of Lymphovascular Invasion in Breast Cancer: Current Evidence, Technical Advances, and Future Directions. [PDF]
Wang H, Huang C, Wang Y, Liu Y.
europepmc +1 more source
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley +1 more source
Detection of neuron specific enolase in the lip and ear pinna of goat (Capra hircus): an immunohistochemical study. [PDF]
Mustafa FEA.
europepmc +1 more source
Vascular Endothelial Growth Factors and the Bmx Tyrosine Kinase in the Regulation of Angiogenesis and Lymphangiogenesis [PDF]
Paavonen, Karri
core
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity. [PDF]
Beech DJ.
europepmc +1 more source
Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin +4 more
wiley +1 more source

