Results 151 to 160 of about 1,625,308 (345)
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source
Is It Possible to Train the Endothelium?—A Narrative Literature Review
LifeThis review provides an overview of current knowledge regarding the adaptive effects of physical training on the endothelium. The endothelium plays a crucial role in maintaining the health of vessel walls and regulating vascular tone, structure, and ...
Karolina Biernat +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue +3 more
wiley +1 more source
ULTRASTRUCTURE OF VASCULAR ENDOTHELIUM IN THE FROG
Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1965 An electron microscopic investigation of the endothelium of capillaries and venules of the frog (Hyla cœrulea) revealed, as well as the usual cytoplasmic constituents, several new features.In the endothelial cells three types of vesicle were encountered, each of which could be highly selective in the transport of materials across the vessel wall.
openaire +3 more sources
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Vascular endothelium - Gatekeeper of vessel health.
Atherosclerosis, 2016 P. Cahill, E. Redmond
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source