Results 211 to 220 of about 1,648,635 (304)

Beyond Diabetes: The Vasculoprotective Effects and Anti-Atherosclerotic Potential of Tirzepatide. [PDF]

Int J Mol Sci
Rzepiński Ł, Tywoniuk A, Jaraczewska J, Al-Shaer A, Wiciński M.   +4 more
europepmc   +1 more source

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Nature, 1999
D. Fulton, J. Gratton, T. Mccabe, J. Fontana, Y. Fujio, K. Walsh, T. Franke, A. Papapetropoulos, W. Sessa   +8 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Pathophysiology of Pulmonary Arterial Hypertension: Focus on Vascular Endothelium as a Potential Therapeutic Target. [PDF]

Int J Mol Sci
Correale M, Mercurio V, Bevere EML, Pezzuto B, Tricarico L, Attanasio U, Raucci A, Ferrara AL, Loffredo S, Puteo C, Iacoviello M, Margaglione M, Brunetti ND, Tocchetti CG, Agostoni P, Mussolino C, Vinci MC.   +16 more
europepmc   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Vasorelaxant effects of the edible flowers <i>Tagetes erecta</i> L. and its possible mechanism of action. [PDF]

Pharm Biol
Núñez S, López V, Arruebo Loshuertos MP, Plaza Carrión MÁ, Gómez-Rincón C, Valero MS.   +5 more
europepmc   +1 more source

Evolutionary origins of the blood vascular system and endothelium

Journal of Thrombosis and Haemostasis, 2013
R. Monahan-Earley, Ann Dvorak, W. Aird, W. Aird   +3 more
semanticscholar   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Saphenous vein graft and nitric oxide: strategies to prevent graft failure and enhance patency in coronary artery bypass grafting. [PDF]

Front Cardiovasc Med
Dell'Aquila M, Prapas S, Falco G, Abdalla S, Tejada B, Challagalla M, Condello I, Newman J, Jarral O, Pupovac S, Ali A, Katsavrias K, D'Onofrio A, Zebele C, Totaro A, Labriola V, Caldonazo T, Kirov H, Di Franco A, Leith J, Rong L, Rahouma M, Brinster D, Iribarne A, Manetta F, Patel N, Kalimi R, Gaudino M, Calafiore AM.   +28 more
europepmc   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source