Results 211 to 220 of about 322,021 (244)
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Vascular Grafts and the Endothelium
Endothelium, 2006This article discusses the importance of the endothelium for successful vascular grafts derived from both native arteries and synthetic materials. It also discusses the fundamental strategies to endothelialize synthetic grafts in animal experiments and in the clinic, as well as the use of endothelial progenitor cells (EPCs), bone marrow-derived cells ...
Hoenig, Michel R. +2 more
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Role of the vascular endothelium
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981The intact vascular endothelial surface is considered to be ‘non-thrombogenic’, and blood platelets usually fail to adhere to it. In this role, the endothelium serves to maintain the integrity of the vascular system by preventing the escape of blood and by preventing the build-up of solid thrombus within the vessel, which would compromise ...
A. A. Brotherton +4 more
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Cryofixation of vascular endothelium
Journal of Electron Microscopy Technique, 1991AbstractCryofixation refers to the immobilization of tissue components by the rapid removal of heat from the specimen, so that the structure is interred and stabilized in a natural embedding medium, namely, frozen (amorphous or microcrystalline) tissue water.
Andrews Sb, Roger C. Wagner
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Estrogens and the Vascular Endothelium
Annals of the New York Academy of Sciences, 2002Abstract: Estrogens exert important regulatory functions on vessel wall components, which may contribute to the increased prevalence and severity of certain chronic inflammatory and autoimmune diseases in females and the lower cardiovascular risk observed in premenopausal women. Endothelial cells have been recently identified as targets for estrogens,
H. William Schnaper +2 more
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The Vascular Endothelium in Hypertension
2006The vascular endothelium plays a fundamental role in the basal and dynamic regulation of the circulation. Thus, it has a crucial role in the pathogenesis of hypertension. A spectrum of vasoactive substances is synthesised in the endothelium; of these, nitric oxide (NO), prostacyclin (PGI2) and endothelin (ET)-1 are the most important.
Lukas E. Spieker +2 more
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Epigenetics of the vascular endothelium
Journal of Applied Physiology, 2010Classical models of transcription in vascular endothelial cells, specifically the cis/trans paradigm, have limitations. For instance, how does the environment have chronic effects on gene expression in endothelial cells after weeks or years? When an endothelial cell divides, how is this information transmitted to daughter cells?
Philip A. Marsden +2 more
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Vascular endothelium in atherosclerosis
Cell and Tissue Research, 2008Their strategic location between blood and tissue and their constitutive properties allow endothelial cells (EC) to monitor the transport of plasma molecules, by employing bidirectional receptor-mediated and receptor-independent transcytosis and endocytosis, and to regulate vascular tone, cellular cholesterol and lipid homeostasis. These cells are also
Anca V. Sima +2 more
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ION CHANNELS IN VASCULAR ENDOTHELIUM
Annual Review of Physiology, 1997▪ Abstract The functional impact of ion channels in vascular endothelial cells (ECs) is still a matter of controversy. This review describes different types of ion channels in ECs and their role in electrogenesis, Ca2+ signaling, vessel permeability, cell-cell communication, mechano-sensor functions, and pH and volume regulation.
Nilius, Bernd +2 more
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Hemodynamics and the Vascular Endothelium
Journal of Biomechanical Engineering, 1993The endothelium, once thought to be a passive, non-thrombogenic barrier, is now recognized as being a dynamic participant in vascular biology and pathobiology. Part of its dynamic nature is due to the influence of the mechanical environment imposed by the hemodynamics of the vascular system.
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The vascular endothelium as an inhibitor of thrombin
Thrombosis Research, 1983Uptake and inhibition of thrombin on the endothelium of porcine aorta was studied in vitro. The thrombin was labelled with 125J and its enzyme activity was measured with an amidolytic assay. After exposure to the aorta both the enzyme activity and radioactivity disappeared from the solution and were recovered as surface bound activities.
M. Dryjski, P. Olsson, Jesper Swedenborg
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