Results 291 to 300 of about 1,625,308 (345)

Vascular Endothelium and Atherosclerosis

2006
Atherosclerosis depends critically on altered behavior of the intrinsic cells of the artery wall, the endothelial cells and smooth muscle cells, and inflammatory leukocytes that join them in the arterial intima during the atherogenic process. The homeostatic properties of the normal endothelium contribute importantly to maintenance of aspects of ...
M. K. Jain, Peter Libby, Masanori Aikawa
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The Vascular Endothelium in Scleroderma

International Reviews of Immunology, 1995
(1995). The Vascular Endothelium in Scleroderma. International Reviews of Immunology: Vol. 12, No. 2-4, pp. 227-245.
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Vascular endothelium: Vasoactive mediators

Progress in Cardiovascular Diseases, 1996
In most blood vessels, the endothelium generates both vasodilator and growth-stabilizing mediators under normal physiological circumstances. The vasodilator influence of the endothelium modulates the vasoconstriction induced by adrenergic nerves, bloodborne substances, and local autacoids.
Vanhoutte, PM, Mombouli, JV
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Vascular endothelium in cancer

Cell and Tissue Research, 2008
The vascular endothelium plays an essential role during organogenesis and in tissue homeostasis. Growing evidence also supports its essential and complex role in tumour biology and cancer progression. In particular, excessive proliferation and transformation or dysfunction of endothelial cells leads to pathological (lymph)angiogenesis or vascular ...
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Neutrophil interactions with the vascular endothelium

International Immunopharmacology, 2013
Neutrophils are a key mediator of the innate immune system and are pivotal in the inflammatory response to infection or tissue damage. Fundamental to the role that neutrophils play in host defence is their interaction with the vascular endothelium. From the initial mobilisation of neutrophils out of the bone marrow to their ultimate transmigration ...
Claudine S. Bonder, David Dimasi, Wai Y. Sun, Wai Y. Sun, Wai Y. Sun   +4 more
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Nitric Oxide and the Vascular Endothelium

2006
The vascular endothelium synthesises the vasodilator and anti-aggregatory mediator nitric oxide (NO) from L-arginine. This action is catalysed by the action of NO synthases, of which two forms are present in the endothelium. Endothelial (e)NOS is highly regulated, constitutively active and generates NO in response to shear stress and other ...
Moncada, S., Higgs, E. A.
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The vascular endothelium in diabetes and hypertension

Journal of Hypertension, 1992
To review recent research into the function of endothelial cells in relation to diabetes and hypertension, and the implications for cardiovascular control.Endothelial cells extract and inactive circulating hormones, convert inactive precursors into vasoactive products, and synthesize and secrete vasodilator and vasoconstrictor mediators, which also ...
Patrick Vallance, Alison Calver, Joe Collier   +2 more
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Tumor Interaction with Vascular Endothelium

Pathophysiology of Haemostasis and Thrombosis, 1987
Clinical and experimental observations suggest that tumor-induced endothelial cell (EC) injury may be one of several initial events in the establishment of tumor metastases. This work investigates tumor-induced EC injury and the interaction between tumor-damaged EC and platelets.
Hamid Al-Mondhiry, Virginia McGarvey
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Vascular Endothelium and Ca2† Antagonists

Journal of Cardiovascular Pharmacology, 1988
Endothelial cells can release both relaxing and contracting factors. Since the release of endothelium-dependent relaxing factor is prevented by incubation in Ca2+-free solution and can be triggered by the Ca2+ ionophore A 23187, it must require an increase in cytoplasmic Ca2+ concentration in the endothelial cells.
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Vascular Endothelium and Blood Flow

2006
Major advances have been made over the last decade towards the elucidation of the molecular mechanisms involved in the endothelium-dependent regulation of vascular tone and blood flow. While the primary endothelium-derived vasodilator autacoid is nitric oxide, it is clear that epoxyeicosatrienoic acids and other endothelium-derived hyperpolarising ...
Ingrid Fleming, Rudi Busse
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