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Veterinary Clinics of North America: Equine Practice, 2003
Although recognition of clinical signs of endotoxemia is not difficult, determining the underlying cause for the development of endotoxemia may be a challenging task. For this reason, importance must be placed on performance of a thorough physical examination, attention to detail, and determination of whether or not surgical intervention is required ...
James N, Moore, Michelle Henry, Barton
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Although recognition of clinical signs of endotoxemia is not difficult, determining the underlying cause for the development of endotoxemia may be a challenging task. For this reason, importance must be placed on performance of a thorough physical examination, attention to detail, and determination of whether or not surgical intervention is required ...
James N, Moore, Michelle Henry, Barton
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ENDOTOXEMIA ALTERS SPLANCHNIC CAPACITANCE
Shock, 2000The splanchnic circulation constitutes a major portion of the total capacitance vasculature and may affect venous return and subsequently cardiac output during low output states. This study assessed the effects of rapid (10 microg/kg over 5 min) and slow (10 microg/kg over 60 min) induction of endotoxin (Escherichia coli) shock on splanchnic blood ...
M R, Ujhelyi +9 more
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Journal of Cardiovascular Pharmacology, 1993
Sepsis leads to changes in blood volume and distribution. In the experiments reported here we monitored circulatory changes during endotoxemia and their relation to portal and systemic levels of endothelin-1 (ET-1). Piglets were monitored cardiovascularly under ketamine anesthesia for 6 h after an endotoxin infusion (saline controls).
U, Myhre +3 more
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Sepsis leads to changes in blood volume and distribution. In the experiments reported here we monitored circulatory changes during endotoxemia and their relation to portal and systemic levels of endothelin-1 (ET-1). Piglets were monitored cardiovascularly under ketamine anesthesia for 6 h after an endotoxin infusion (saline controls).
U, Myhre +3 more
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Archives of Dermatology, 1982
To the Editor.— We have been able to detect circulating endotoxin in six of 11 patients with psoriasis. Our interest in the possibility of endotoxemia in psoriasis followed recent demonstrations of alterations in levels of alternative complement pathway components 1 and of circulating IgA immune complexes in psoriasis.
P W, Belew +3 more
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To the Editor.— We have been able to detect circulating endotoxin in six of 11 patients with psoriasis. Our interest in the possibility of endotoxemia in psoriasis followed recent demonstrations of alterations in levels of alternative complement pathway components 1 and of circulating IgA immune complexes in psoriasis.
P W, Belew +3 more
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Calcium overload in endotoxemia
Life Sciences, 1981Abstract E.coli endotoxin stimulates endogenous lipolysis in the in vitro perfused rat heart. Verapamil® inhibits endotoxin- (as well as glucagon-) stimulated lipolysis. This suggests that the endotoxin used increases the availability of Ca++ to the lipolytic system in the cardiocytes. This conclusion is supported by the observed stimulation of
W C, Hülsmann +3 more
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Endotoxemia in experimental acholia
Bulletin of Experimental Biology and Medicine, 1997The intensity of experimental endotoxemia is assessed by serum content of medium molecules. Serum creatinine and bilirubin contents and leukocyte count are also monitored. It is found that acholia leads to pronounced endogenous intoxication which can be prevented by early return of bile into the organism.
A N, Popov, M M, Minnebaev
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ENDOTOXEMIA IN HUMAN SEPTIC SHOCK
Critical Care Medicine, 1988To evaluate the incidence, pattern and clinical importance of endotoxemia in septic shock, frequent, serial endotoxin determinations were made prospectively in patients with shock. Detectable endotoxin occurred in 43 of 100 patients with septic shock, but in only one of ten patients with shock due to nonseptic causes.
R L, Danner +5 more
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New England Journal of Medicine, 1973
Endotoxins — lipopolysaccharides that form a portion of the cell walls of gram-negative bacteria — cause alterations of blood coagulation, complement and kallikrein, and often hypotension and death in a variety of laboratory animals.1 Endotoxin has been considered a likely cause of some of the pathophysiological alterations that often lead to death of ...
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Endotoxins — lipopolysaccharides that form a portion of the cell walls of gram-negative bacteria — cause alterations of blood coagulation, complement and kallikrein, and often hypotension and death in a variety of laboratory animals.1 Endotoxin has been considered a likely cause of some of the pathophysiological alterations that often lead to death of ...
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American Journal of Physiology-Heart and Circulatory Physiology, 2005
Endocannabinoids and CB1 receptors have been implicated in endotoxin (LPS)-induced hypotension: LPS stimulates the synthesis of anandamide in macrophages, and the CB1 antagonist SR-141716 inhibits the hypotension induced by treatment of rats with LPS or LPS-treated macrophages.
S. M. Gardiner, T. Bennett
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Endocannabinoids and CB1 receptors have been implicated in endotoxin (LPS)-induced hypotension: LPS stimulates the synthesis of anandamide in macrophages, and the CB1 antagonist SR-141716 inhibits the hypotension induced by treatment of rats with LPS or LPS-treated macrophages.
S. M. Gardiner, T. Bennett
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Gastrointestinal myoelectric activity during endotoxemia
The American Journal of Surgery, 1996Gastrointestinal myoelectric activity during postoperative ileus has been well characterized. However, the common clinical scenario of ileus occurring during and after episodes of sepsis is not well understood. The aim of our study was to determine the effects of a single, sublethal dose of endotoxin on canine gastrointestinal myoelectric activity ...
J J, Cullen +2 more
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