Results 21 to 30 of about 62,922 (266)
Journal of Veterinary Internal Medicine, 2020 Background Little information is available about endotoxemia in donkeys. Characterizing the systemic inflammatory response (SIRS) to lipopolysaccharide (LPS) in donkeys would provide valuable clinical and therapeutic information. The effects of meloxicam
Francisco Javier Mendoza Garcia +4 more
doaj +1 more source
Development and Characterization of an Endotoxemia Model in Zebra Fish
Frontiers in Immunology, 2018 Endotoxemia is a condition in which endotoxins enter the blood stream and cause systemic and sometimes lethal inflammation. Zebra fish provides a genetically tractable model organism for studying innate immunity, with additional advantages in live ...
Alan Y. Hsu +13 more
doaj +1 more source
Endotoxemia is associated with an adverse metabolic profile
Innate Immunity, 2021 Our aim was to analyze whether endotoxemia, i.e. translocation of LPS to circulation, is reflected in the serum metabolic profile in a general population and in participants with cardiometabolic disorders. We investigated three Finnish cohorts separately
Anne-Mari Määttä +9 more
doaj +1 more source
Endotoxemia in Patients with Liver Cirrhosis
Aktualʹnaâ Infektologiâ, 2015 There is a relationship between infection and the severity of endotoxemia in patients with liver cirrhosis (LC). Bacterial or viral or agent, penetrating the body of a patient with LC, triggers a cascade of immune-enzymatic reactions resulting in the ...
O.N. Domashenko +3 more
doaj +1 more source
Frontiers in Nutrition, 2022 Obesity has become a public health concern due to its global prevalence and high risk of complications such as endotoxemia. Given the important role of gut microbiota in obesity, probiotics targeting gut microbiota have been developed and applied to ...
Xiaokang Niu +9 more
doaj +1 more source
The microcirculation during endotoxemia [PDF]
Cardiovascular Research, 1996 The initial responses to endotoxemia are detectable in the microcirculation as a microvascular inflammatory response characterized by activation of the endothelium stimulating these cells from their normal anticoagulant state to a procoagulant state with increased adhesiveness for leukocytes and platelets.
R S, McCuskey +2 more
openaire +2 more sources
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome [PDF]
, 2013 Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans.
Beaulieu E +12 more
core +2 more sources
Beta-glucan reflects liver injury after preservation and transplantation in dogs. [PDF]
, 1999 Graft failure and extrahepatic organ complications, which frequently develop after transplantation, may be related to inflammatory mediators stimulated by endotoxin (ET). The role of endotoxemia after liver transplantation is controversial and may depend
Azoulay D +23 more
core +1 more source
Gut Microbes, 2021 Gasdermin D (GSDMD) functions as a key pyroptotic executor through its secreted N-terminal domain (GSDMD-N). However, the functional relevance and mechanistic basis of the precise roles of host colonic GSDMD in high-fat diet (HFD)-induced gut dysbiosis ...
Yujie Shi +8 more
doaj +1 more source
Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury. [PDF]
, 2006 Activated protein C (APC) has emerged as a novel therapeutic agent for use in selected patients with severe sepsis, even though the mechanism of its benefit is not well established.
Looney, Mark R, Matthay, Michael A
core +2 more sources