Results 21 to 30 of about 54,513 (224)

Development and Characterization of an Endotoxemia Model in Zebra Fish

Frontiers in Immunology, 2018
Endotoxemia is a condition in which endotoxins enter the blood stream and cause systemic and sometimes lethal inflammation. Zebra fish provides a genetically tractable model organism for studying innate immunity, with additional advantages in live ...
Alan Y. Hsu, Theodore Gurol, Tiago J. P. Sobreira, Sheng Zhang, Sheng Zhang, Natalie Moore, Chufan Cai, Zhong-Yin Zhang, Zhong-Yin Zhang, Zhong-Yin Zhang, Zhong-Yin Zhang, Qing Deng, Qing Deng, Qing Deng   +13 more
doaj   +1 more source

Is there NO treatment for severe sepsis? [PDF]

, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Endotoxemia in Patients with Liver Cirrhosis

Aktualʹnaâ Infektologiâ, 2015
There is a relationship between infection and the severity of endotoxemia in patients with liver cirrhosis (LC). Bacterial or viral or agent, penetrating the body of a patient with LC, triggers a cascade of immune-enzymatic reactions resulting in the ...
O.N. Domashenko, N.V. Maksimtseva, D.S. Paniieva, D.M. Popova   +3 more
doaj   +1 more source

The microcirculation during endotoxemia [PDF]

Cardiovascular Research, 1996
The initial responses to endotoxemia are detectable in the microcirculation as a microvascular inflammatory response characterized by activation of the endothelium stimulating these cells from their normal anticoagulant state to a procoagulant state with increased adhesiveness for leukocytes and platelets.
R S, McCuskey, R, Urbaschek, B, Urbaschek   +2 more
openaire   +2 more sources

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome [PDF]

, 2013
Natural variation for LPS-induced lethal inflammation in mice is useful for identifying new genes that regulate sepsis, which could form the basis for novel therapies for systemic inflammation in humans.
Beaulieu E, Carlo Riccardi, Claude Libert, Eddleston J, Filip Van Hauwermeiren, Ioanna Petta, Iris Pinheiro, Leen Puimège, Lien Dejager, Marlies Ballegeer, Marnik Vuylsteke, Sofie Vandevyver, Tina Mahieu   +12 more
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Bifidobacterium animalis subsp. lactis MN-Gup protects mice against gut microbiota-related obesity and endotoxemia induced by a high fat diet

Frontiers in Nutrition, 2022
Obesity has become a public health concern due to its global prevalence and high risk of complications such as endotoxemia. Given the important role of gut microbiota in obesity, probiotics targeting gut microbiota have been developed and applied to ...
Xiaokang Niu, Nana Zhang, Shusen Li, Ning Li, Ran Wang, Qi Zhang, Jingjing He, Erna Sun, Xiaohong Kang, Jing Zhan   +9 more
doaj   +1 more source

Beta-glucan reflects liver injury after preservation and transplantation in dogs. [PDF]

, 1999
Graft failure and extrahepatic organ complications, which frequently develop after transplantation, may be related to inflammatory mediators stimulated by endotoxin (ET). The role of endotoxemia after liver transplantation is controversial and may depend
Azoulay D, Bion JF, Blanot S, Clavien PA, Goto M, Hamilton G, Hodes DS, Kambayashi J, Kikuchi M, Levin J, Miyata T, Ruiz-Herrera J., Shuji Matsura, Starzl TE, Steininger R, Tadashi Katsuramaki, Tomomi Suzuki,, , Tanaka S, The Iwanaga S., Todo S, Yokoyama I, Yoshioka T, Zhang GH, Zhang GH, Zhu Y   +23 more
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Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz, Barry BE, Bevilacqua MP, Body SC, Brunk DK, Deuel TF, Dore M, Feuerhake F, Forde RC, Frenette PS, Greenberg AW, Handa K, Hattori R, Heffner JE, Kai Heckel, Kiefmann R, Kubes P, Kubo H, Kuebler WM, Kuhnle GE, Kuhnle GE, Kuklin V, Leo R, Ley K, Li N, Martina Dörger, Massberg S, Matsui NM, Okada Y, Parish CR, Piccardoni P, Rainer Kiefmann, Rinko LJ, Rodgers SD, Ruf A, Sonja Schenkat, Wang L, Williams MJ   +37 more
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Fucoidan Extracted from Fucus evanescens Prevents Endotoxin-Induced Damage in a Mouse Model of Endotoxemia

Marine Drugs, 2014
An important problem of treating patients with endotoxemia is to find drugs to reduce the negative effects of endotoxin on the organism. We tested fucoidan (sulfated polysaccharide) from the brown alga Fucus evanescens as a potential drug in a mouse ...
Tatyana A. Kuznetsova, Natalya N. Besednova, Larisa M. Somova, Natalya G. Plekhova   +3 more
doaj   +1 more source

Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice

Gut Microbes, 2021
Gasdermin D (GSDMD) functions as a key pyroptotic executor through its secreted N-terminal domain (GSDMD-N). However, the functional relevance and mechanistic basis of the precise roles of host colonic GSDMD in high-fat diet (HFD)-induced gut dysbiosis ...
Yujie Shi, Yixin Zou, Yonghong Xiong, Shiyao Zhang, Mingming Song, Xiaofei An, Chang Liu, Wenxiang Zhang, Siyu Chen   +8 more
doaj   +1 more source