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Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. [PDF]
PLoS ONE, 2013 RationaleEndotoxin is a near ubiquitous environmental exposure that that has been associated with both asthma and chronic obstructive pulmonary disease (COPD). These obstructive lung diseases have a complex pathophysiology, making them difficult to study
Peggy S Lai +10 more
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Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies [PDF]
Cardiovascular Diabetology, 2009 Introduction Chronic low-grade inflammation is a significant factor in the development of obesity associated diabetes. This is supported by recent studies suggesting endotoxin, derived from gut flora, may be key to the development of inflammation by ...
Kumar Sudhesh +7 more
doaj +5 more sources
Identification of the Need for a Comprehensive Investigation of Endotoxin in Water Sources [PDF]
Sustainable Earth Trends, 2023 With the increase of global environmental concerns, the importance of emerging pollutants is increasing daily. Endotoxin is one of the emerging pollutants whose presence in water sources causes serious risks to human health.
Reyhane Dehghan +2 more
doaj +1 more source
c-Myb Dominates TBK1-Mediated Endotoxin Tolerance in Kupffer Cells by Negatively Regulating DTX4
Journal of Immunology Research, 2023 As a protective mechanism regulating excessive inflammation, endotoxin tolerance plays a vital role in regulating endotoxin shock. Kupffer cells are players in mediating endotoxin tolerance.
Yi-Lin Wu +4 more
doaj +1 more source
Fish and Shellfish Immunology Reports, 2021 Endotoxin, the outer cell wall membrane lipopolysaccharide component of the Gram-negative bacteria is a factor responsible for a number of complications/disorders and plays important role in the associated with pathophysiological complications and ...
S.K. Nayak, N. Jahan, S. Pattnaik
doaj +1 more source
Comparison of LAL and rFC Assays—Participation in a Proficiency Test Program between 2014 and 2019
Microorganisms, 2020 Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical industries. Suitable compendial assays are defined by national pharmacopoeias. At this time, Limulus Amoebocyte Lysate (LAL) assays are the gold standard. LAL is used
Maike Piehler +3 more
doaj +1 more source
Scientific Reports, 2023 A newly developed semi-automatic synthetic luminescence substrate (SALS) method for measuring endotoxin was compared with the existing turbidimetric kinetic assay (TKA) using leukocyte-rich plasma to verify its usefulness.
Mari Terayama +6 more
doaj +1 more source
Endotoxins Affecting Human Health during Agricultural Practices: An Overview
AppliedChem, 2022 Agricultural operations and the processing sector generate dust laden with endotoxin in the workplace. Endotoxin, a pro-inflammatory agent, has adverse effects on health, especially in the lungs, as exposure to endotoxin reduces lung function capacity ...
B. Surya Kumar Chhetry +3 more
doaj +1 more source
Vaccines, 2020 Cross-presentation in dendritic cells (DC) requires the endosomal relocations of internalized antigens and the endoplasmic reticulum protein Sec61. Despite the fact that endotoxin-containing pathogen and endotoxin-free antigen have different effects on ...
Dan Dan Xu +4 more
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Effect of Food Endotoxin on Infant Health
Toxins, 2021 Endotoxin is a complex molecule derived from the outer membrane of Gram-negative bacteria, and it has strong thermal stability. The processing of infant food can kill pathogenic bacteria but cannot remove endotoxin.
Haoming Wu +5 more
doaj +1 more source