Results 41 to 50 of about 39,562 (267)

The endotoxin of the meningococcus [PDF]

Journal of Hygiene, 1937
1. The view is advanced that the endotoxin of the meningococcus is one of a group of thermostable intracellular bacterial poisons, and that it is not a specific antigenic toxin. 2. The inability of the “endotoxin” to function as an antigen does not lessen its importance as a pathogenic factor in cerebrospinal fever, since the lesions that are ...
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

Advanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong, Bastien Schyrr, Stella Laperrousaz, Hritwick Banerjee, Andreas Leber, Fabien Sorin   +5 more
wiley   +1 more source

Detection of endotoxins from selected drinking water microbiota using an LAL-based assay and its implications for human health

Journal of Water and Health
Endotoxins are pyrogenic lipopolysaccharides from Gram-negative bacteria that are known to induce fever, septic shock, and multiple organ failure, posing a substantial risk to human health.
Harmen Hawer, Rebecca Burmester, Nadine Sonnenberg, Katja Weiß   +3 more
doaj   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Correlation of caecal microbiome endotoxins genes and intestinal immune cells in Eimeria tenella infection based on bioinformatics

Frontiers in Cellular and Infection Microbiology
IntroductionThe infection with Eimeria tenella (ET) can elicit expression of various intestinal immune cells, incite inflammation, disrupt intestinal homeostasis, and facilitate co-infection with diverse bacteria.
Mingzheng Han, Jiale Li, Yijin Wu, Jianzhao Liao   +3 more
doaj   +1 more source

Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix

Journal of Lipid Research, 2010
Timely sensing of lipopolysaccharide (LPS) is critical for the host to fight invading Gram-negative bacteria. We recently showed that apolipoprotein CI (apoCI) (apoCI1–57) avidly binds to LPS, involving an LPS-binding motif (apoCI48–54), and thereby ...
Jimmy F.P. Berbée, Claudia P. Coomans, Marit Westerterp, Johannes A. Romijn, Louis M. Havekes, Patrick C.N. Rensen   +5 more
doaj   +1 more source

Prevalence of Mycotoxins and Endotoxins in Total Mixed Rations and Different Types of Ensiled Forages for Dairy Cows in Lithuania

Toxins, 2021
In this study, 119 samples of total mixed rations and different types of ensiled forage (maize and grass silage, and haylage) collected in 2019–2020 from dairy farms in Lithuania were analyzed to evaluate the quantitative occurrence of mycotoxins and ...
Gintarė Vaičiulienė, Bronius Bakutis, Jurgita Jovaišienė, Rimvydas Falkauskas, Gediminas Gerulis, Sigita Kerzienė, Violeta Baliukonienė   +6 more
doaj   +1 more source