Determination of quasi-primary odors by endpoint detection [PDF]
Scientific Reports, 2021 It is known that there are no primary odors that can represent any other odors with their combination. Here, we propose an alternative approach: “quasi” primary odors.
Hanxiao Xu +7 more
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Model-Based Product Temperature and Endpoint Determination in Primary Drying of Lyophilization Processes [PDF]
Pharmaceutics, 2022 Lyophilization process design still relies mainly on empirical studies with high experimental loads. In the regulatory demanded Quality by Design approach, process modeling is a key aspect.
Alex Juckers +3 more
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Posterior endpoint determination of the lumbar pedicle central axis on the anterior–posterior fluoroscopic image for pedicle screw insertion [PDF]
Scientific ReportsThe transpedicular procedure has been widely used in spinal surgery. The determination of the best entry point is the key to perform a successful transpedicular procedure.
Jun Zhang +3 more
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Burrowing Behavior as Robust Parameter for Early Humane Endpoint Determination in Murine Models for Pancreatic Cancer [PDF]
AnimalsDue to late-stage diagnoses and limited treatment options, pancreatic cancer is predicted to be the second leading cause of cancer deaths by 2030. Many different murine models were developed over the past decades to test new therapies for this tumor ...
Jakob Brandstetter +8 more
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Evaluation of Endpoints for Antifungal Susceptibility Determinations with LY303366 [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT We have previously reported poor correlation between the in vitro fungicidal activity of LY303366 and MIC results in RPMI medium based upon the manufacturer’s suggested susceptibility endpoint, lack of visual growth. Additionally, we have noted a significant trailing effect with LY303366 when MICs are determined in RPMI ...
Michael E. Klepser +4 more
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Vertebral Heart Score: A Useful Parameter in Determination of Resuscitation Endpoint in Dogs with Hemorrhagic Shock [PDF]
Iranian Journal of Veterinary Medicine, 2019 BACKGROUND: GReliable prediction of patient response to fluid resuscitation is a crucial issue in the management of hemorrhagic shock. OBJECTIVES: This study was designed to investigate vertebral heart score (VHS) variation in fluid resuscitation of ...
Reza Azargoun +4 more
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Sample size determination for time-to-event endpoints in randomized selection trials with generalized exponential distribution [PDF]
HeliyonRandomized selection trials are frequently used to compare experimental treatments that have the potential to be beneficial, but they often do not include a control group.
Muhammad Hamza Akbar +3 more
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Determination of 50% endpoint titer using a simple formula
World Journal of Virology, 2016 Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed.
Muthannan Andavar Ramakrishnan
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A rational approach of early humane endpoint determination in a murine model for cholestasis
ALTEX, 2019 Reduction of animal suffering during in vivo experiments is usually ensured by continuously monitoring the health status using a score sheet and by applying humane endpoints. However, most studies do not evaluate the plausibility of score sheets and do not attempt to reduce the suffering of animals by determining earlier and, therefore, more humane ...
Xianbin Zhang
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Evaluation of Event-Free Survival as a Surrogate Endpoint for Overall Survival in Muscle-Invasive Bladder Cancer Following Neoadjuvant Treatment: A Systematic Review and Meta-Analysis [PDF]
Oncology and TherapyIntroduction Event-free survival (EFS), a common endpoint in neoadjuvant/perioperative oncology trials, allows for accelerated treatment evaluation while awaiting results of overall survival (OS).
Cora N. Sternberg +6 more
doaj +2 more sources