Results 101 to 110 of about 176,455 (318)

Precision SUSY Measurements at LHC [PDF]

, 1996
If supersymmetry exists at the electroweak scale, then it should be discovered at the LHC. Determining masses, of supersymmetric particles however, is more difficult.
A. Bartl, A. Gabutti, A. H. Chamseddine, F. Abe, F. Abe, F. Abe, F. E. Paige, F. Paige, H. Baer, H. Baer, H. Baer, H. P. Nilles, I. Hinchliffe, J. Ellis, J. Söderqvist, K. Inoue, L. Alvarez-Gaume, L. Ibañez, L. J. Hall, M. D. Shapiro, S. Abachi, S. Abachi, W. Yao   +22 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Kinematic Edges with Flavor Splitting and Mixing

, 2012
The kinematic edges of invariant mass distributions provide an important tool for the possible measurements of superpartner masses in supersymmetric models with a neutralino LSP.
Galon, Iftah, Shadmi, Yael
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Determination of potential thresholds for N-ethyl-N-nitrosourea and ethyl methanesulfonate based on a multi-endpoint genotoxicity assessment platform in rats [PDF]

, 2022
Xuejiao Zhu, Jiao Huo, Zhu Zeng, Yunjie Liu, Ruirui Li, Yiyi Chen, Lishi Zhang, Jinyao Chen   +7 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

An AIE-active probe acts as novel tool for rapid and accurate quantitative antifungal susceptibility assessment

Frontiers in Microbiology
ObjectivesCommon antifungal susceptibility testing methods are often time-consuming and subject to interpretation bias in endpoint determination, making them inadequate for clinical applications. We aim to develop a rapid and accurate quantitative method
Fen Zheng, Fen Zheng, Xiaoxue Ge, Yajuan Guan, Qixian Zhou, Renren Shi, Jiayi Zhao, Bo Situ, Jing Zhang, Yongyu Rui   +9 more
doaj   +1 more source

Mass Measurement Using Energy Spectra in Three-body Decays

, 2015
In previous works we have demonstrated how the energy distribution of massless decay products in two body decays can be used to measure the mass of decaying particles.
Agashe, Kaustubh, Franceschini, Roberto, Kim, Doojin, Wardlow, Kyle   +3 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source