Results 111 to 120 of about 447,247 (352)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Energetic derivatives of 3,3′,5,5′-tetranitro-4,4′-bipyrazole (TNBPz): Synthesis, characterization and properties

FirePhysChem
3,3‘,5,5‘-Tetranitro-4,4‘-bipyrazole monohydrate (TNBPz, 1⋅H2O) is an excellent precursor for the synthesis of new energetic materials (2–12). Several nitrogen-rich salts (e.g.
Ivan Gospodinov, Kostiantyn V. Domasevitch, Cornelia C. Unger, Maximilian Benz, Jörg Stierstorfer, Thomas M. Klapötke   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

N-Acetonitrile functionalized 3-nitrotriazole: Precursor to nitrogen rich stable and insensitive energetic materials

Energetic Materials Frontiers
In the field of energetic materials, prime attention has been given to the synthesis of environmentally compatible energetic materials having an adequate balance between energy and stability.
Prachi Bhatia, Peddapothula Sahithi Priya, Priyanka Das, Dheeraj Kumar   +3 more
doaj   +1 more source

Trigger linkage mechanism: Two or multiple steps initiate the spontaneous decay of energetic materials

, 2022
Ying Xiong, Kai Zhong, Chaoyang Zhang
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Probing the effect of activated carbon-based metal oxides on the thermocatalytic decomposition of energetic NC-DEGDN formulation

FirePhysChem
This study investigate the catalytic behavior of activated carbon-supported metal oxides on the thermal decomposition of a double-base propellant comprising nitrocellulose (NC) and diethylene glycol dinitrate (DEGDN).
Mohammed Dourari, Ahmed Fouzi Tarchoun, Djalal Trache, Yasmine Boutillara, Amir Abdelaziz, Roufaida Tiliouine, Tessnim Barkat, Fateh Chalgoum, Yash Pal, Weiqiang Pang   +9 more
doaj   +1 more source

A Study on Development of Reaction Rate Equation for Reactive Flow Simulation in Energetic Materials [PDF]

, 2012
Bohoon Kim, Jai-ick Yoh
openalex   +1 more source

Influence of nitroamino−nitroimino tautomerism: A useful theoretical supplement for nitroamino-based energetic materials

, 2023
Yaxi Wang, Xun Zhang, Jun‐Liang Liu, Meng-xin Xue, Lu Hu, Siping Pang   +5 more
openalex   +1 more source