Results 111 to 120 of about 6,576,691 (245)

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Phytochemicals from as potential tumor necrosis factor-alpha inhibitors: A computational study

Journal of Chemical Research
Molecular docking and molecular dynamics simulations were employed to screen plant-derived compounds from Aralia armata for potential inhibition of tumor necrosis factor-alpha (PDB ID: 2AZ5). Aralia armata has a history of use in traditional medicine and
Vu Thi Thu Le, Luc Quang Tan, Do Khac Hung, Nguyen Xuan Ha   +3 more
doaj   +1 more source

Chagas disease induces gut microbial metabolic stress: Disruption of energy and nucleotide pathways and partial reversal by antiparasitic therapy (TRIPOBIOME-2 study)

Travel Medicine and Infectious Disease
Chagas disease (CD) can alter gut microbiota composition, although its functional impact is poorly defined. We conducted whole-genome metagenomic sequencing of stool samples from 55 adults with chronic CD (23 treated with benznidazole) and 17 non ...
José A. Pérez-Molina, Elena Moreno, Clara Crespillo-Andújar, Sandra Chamorro-Tojeiro, Marta Arsuaga, Leticia Olavarrieta, Oihane Martín, Begoña Monge-Maillo, Francesca Norman, Val F. Lanza, Sergio Serrano-Villar   +10 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Agrobacterium mediated manipulation of the expression of an polysaccharide biosynthetic phosphoglucose isomerase gene to improve polysaccharide production in Sanghuangporus vaninii

Food Chemistry: Molecular Sciences
The Sanghuangporus vaninii polysaccharide plays diverse biological roles in enhancing human health; nonetheless, the fundamental process of polysaccharide synthesis in S. vaninii remains unclear.
Zihao Li, Weihang Li, Yi Zhou, Congtao Xu, Jinlong Pan, Yajie Zou   +5 more
doaj   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Zero energy homes: Combining energy efficiency and solar energy technologies

, 2000
In a typical Florida house, air-conditioning accounts for about 35% of all the electricity the home uses. As the largest single source of energy consumption in Florida, a home's air-conditioning load represents the biggest energy challenge facing Florida
National Renewable Energy Laboratory (U.S.)
core  

Computed Tomography‐ and Photoacoustic Imaging‐Active Bioresorbable Electrospun Bismuth Nanoparticle‐Infused Small‐Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena, Joy Vanessa D. Perez, Marvin R. Bernardino, Dominic Karl M. Bolinas, Kitz Paul D. Marco, Kim Claudette J. Fernandez, Archana Mishra, Erin Marie D. San Valentin, Jossana A. Damasco, Gino Martin Canlas, Natalie Fowlkes, Richard R. Bouchard, Steven Y. Huang, Marites P. Melancon   +13 more
wiley   +1 more source

Effects of Supplementation with Essential Fatty Acids and Conjugated Linoleic Acids on Muscle Structure and Fat Deposition in Lactating Holstein Cows

Agriculture
High-yielding dairy cows need diets that meet their energy demand and contain sufficient essential nutrients such as n-3 fatty acids (FAs). Conjugated linoleic acid (CLA) is able to relieve the energy metabolism, but common corn silage and concentrate ...
Cheng Xiao, Elke Albrecht, Dirk Dannenberger, Weibo Kong, Hao Gu, Harald M. Hammon, Steffen Maak   +6 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source