Results 121 to 130 of about 2,199,245 (317)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Demonstration of Selective Catalytic Reduction Technology to Control Nitrogen Oxide Emissions From High-Sulfur, Coal-Fired Boilers: A DOE Assessment [PDF]

open access: yes, 1999
The goal of the U.S. Department of Energy (DOE) Clean Coal Technology (CCT) program is to furnish the energy marketplace with a number of advanced, more efficient, and environmentally responsible coal utilization technologies through demonstration ...
Federal Energy Technology Center (U.S.)
core   +1 more source

A Primer on Energy Conditions [PDF]

open access: yes, 2017
An energy condition, in the context of a wide class of spacetime theories (including general relativity), is, crudely speaking, a relation one demands the stress-energy tensor of matter satisfy in order to try to capture the idea that "energy should be positive".
openaire   +3 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A Synthetic Null Energy Condition

open access: yesCommunications in Mathematical Physics
We give a simplified approach to Kunzinger & Saemann's theory of Lorentzian length spaces in the globally hyperbolic case; these provide a nonsmooth framework for general relativity. We close a gap in the regularly localizable setting, by showing consistency of two potentially different notions of timelike geodesic segments used in the literature ...
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Atomic Energy Commission Report WASH-1224

open access: yes, 1974
From preface: This study is an attempt to quantify societal costs associated with the production of electrical energy by currently available alternative systems under routine operating ...
U.S. Atomic Energy Commission. Office of Energy Systems Analysis.   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tribological design constraints of marine renewable energy systems

open access: yes, 2010
Against the backdrop of increasing energy demands, the threat of climate change and dwindling fuel reserves, finding reliable, diverse, sustainable/renewable, affordable energy resources has become a priority for many countries.
AbuBakr S. Bahaj   +11 more
core   +1 more source

Averaged energy conditions and bouncing universes [PDF]

open access: yesPhysical Review D, 2017
The dynamics of bouncing universes is characterized by violating certain coordinate invariant restrictions on the total energy-momentum tensor, customarily referred to as energy conditions. Although there could be epochs where the null energy condition is locally violated, it may perhaps be enforced in an averaged sense.
openaire   +2 more sources

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