Results 141 to 150 of about 10,480,065 (303)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Solid state optical conjugated polymer amplifier; with ultrafast gain switching

open access: yes, 2008
Conjugated polymers are organic materials which are attractive as optoelectronic devices because they have a combination of broad band emission, high gain, versatility in processing, are ductile and can be electrically pumped.
Amarasinghe, Dimali C. V.
core  

If there is dissipation the particle can gain energy

open access: yesJournal of Physics: Conference Series, 2015
In this work, we summarize two different mechanisms to gain energy from the presence of dissipation in a time-dependent non-linear system. The particles can gain energy, in the average, from two different scenarios: i) for very week dissipation with the creation of an attractor with high velocity, and ii) in the opposite limit, for very strong ...
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

LEAP Phase II, Net Energy Gain From Laser Fields in Vacuum [PDF]

open access: yes, 2005
The current Laser Electron Acceleration Program (LEAP) seeks to modulate the energy of an electron bunch by interaction of the electrons with a copropagating pair of crossed laser beams at 800 nm.
Plettner, T.   +3 more
core  

Computation of time energy gain in D-3He mixture: Energy deposited through deuterium ignition beam

open access: yes, 2014
The fast ignition approach to ICF consists in first compressing the fuel to high density by a suitable driver and then creating the hot spot required for ignition by means of a second external pulse.
Hosseinimotlagh, S. N.   +1 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Gaining energy from sunlight [PDF]

open access: yes, 2014
Die vorliegende Dissertation gliedert sich in zwei Teile. Im ersten Teil werden Synthesen und Charakterisierungen von metallorganischen MOCVD-Precusoren des Molybdäns und Wolframs beschrieben (einschließlich bisher unbekannter metallorganisch / organischer Zwischen- und Nebenprodukte).
openaire  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Understanding the effect of sex on energy requirements of hair sheep

open access: yesAnimal
Differences and/or similarities in the influence of sex class for hair sheep requirements remain inconclusive. Knowledge of energy requirements allows well-formulated diets to be provided which is crucial for improving animal production.
C.J.L. Herbster   +11 more
doaj   +1 more source

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