Results 111 to 120 of about 981,494 (350)

Energy Homeostasis and Kisspeptin System, Roles of Exercise and Outcomes with a Focus on Male Reproductive Health

Endocrines
Background: Obesity is a multisystemic health problem causing chronic diseases like diabetes or cardiovascular diseases, but also reproductive dysfunctions like infertility in adults or altered puberty onset in children.
Mario Ruggiero, Antonella Vicidomini, Domenico Tafuri, Filomena Mazzeo, Rosaria Meccariello   +4 more
doaj   +1 more source

The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors

Frontiers in Systems Neuroscience, 2017
The melanin-concentrating hormone (MCH) is an important peptide implicated in the control of motivated behaviors. History, however, made this peptide first known for its participation in the control of skin pigmentation, from which its name derives.
Giovanne B. Diniz, Jackson C. Bittencourt, Jackson C. Bittencourt   +2 more
doaj   +1 more source

Pituitary adenylate cyclase-activating polypeptide receptor activation in the hypothalamus recruits unique signaling pathways involved in energy homeostasis

, 2022
Brian Maunze, Katherine Wood Bruckner, Nikhil Nilesh Desai, Christopher Chen, Fanghong Chen, David Baker, SuJean Choi   +6 more
openalex   +2 more sources

Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats [PDF]

, 2021
Mohammed K. Hankir, Laura Rotzinger, Arno Nordbeck, Caroline Corteville, Ulrich Dischinger, Juna‐Lisa Knop, Annett Hoffmann, Christoph Otto, Florian Seyfried   +8 more
openalex   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Sex-Specific Role of NPVF Signalling in Homeostatic Control

Biomolecules
Neuropeptide VF (NPVF) is a member of the RFamide family of peptides and is suggested to be involved in homeostatic regulations. However, direct evidence is sparse. Here, we generated a NPVF knockout mouse model to comprehensively investigate its role in
Herbert Herzog, Julia Koller, Lei Zhang
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Biochemical and Metabolic Characterization of the Manila Clam Ruditapes philippinarum in Response to Different Frozen Concentrated Microalgal Diets

Fishes
This study evaluated the effects of different frozen concentrated microalgal feeds and their mixtures on the growth, digestive enzyme activity, biochemical composition, and metabolomic profiles of adult Manila clams, Ruditapes philippinarum, aiming to ...
Jianfeng Ding, Borui Li, Yanfeng Lu, Yuyang Xiong, Tong Chen, Yanqin Ma, Dongdong Li, Zhongming Huo   +7 more
doaj   +1 more source

Control of energy homeostasis by amylin [PDF]

, 2018
Amylin is an important control of nutrient fluxes because it reduces energy intake, modulates nutrient utilization by inhibiting postprandial glucagon secretion, and increases energy disposal by preventing compensatory decreases of energy expenditure in ...
Lutz, Thomas
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source