Results 41 to 50 of about 369,179 (266)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Animal, 2015 Play behaviour has been proposed as a measure of good welfare in growing animals and locomotor play by calves is often reduced after weaning off milk.
G.G. Miguel-Pacheco +3 more
doaj +1 more source
Healthcare-associated infections are associated with insufficient dietary intake: an observational cross-sectional study. [PDF]
PLoS ONE, 2015 Indicators to predict healthcare-associated infections (HCAI) are scarce. Malnutrition is known to be associated with adverse outcomes in healthcare but its identification is time-consuming and rarely done in daily practice.
Ronan Thibault +8 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Parent Diet Quality and Energy Intake Are Related to Child Diet Quality and Energy Intake [PDF]
Journal of the Academy of Nutrition and Dietetics, 2016 Parents' diets are believed to influence their children's diets. Previous studies have not adequately and simultaneously assessed the relationship between parent and child total diet quality and energy intakes.Our aim was to investigate whether parent and child diet quality and energy intakes are related.We conducted a cross-sectional analysis using ...
Shannon M. Robson +6 more
openaire +4 more sources
Ecology and EvolutionAnimal energy intake and expenditure strategies in response to environmental fluctuations have been widely studied. Optimal foraging theory (OFT) is the dominant framework in this field; however, studies addressing the OFT in endangered waterbird species
Chao Yu +7 more
doaj +1 more source
Acutely decreased thermoregulatory energy expenditure or decreased activity energy expenditure both acutely reduce food intake in mice. [PDF]
PLoS ONE, 2012 Despite the suggestion that reduced energy expenditure may be a key contributor to the obesity pandemic, few studies have tested whether acutely reduced energy expenditure is associated with a compensatory reduction in food intake.
Karl J Kaiyala +6 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Journal of Nutrition, Health and AgingObjectives: Findings regarding dietary protein and frailty are inconsistent. This inconsistency may be attributed to variations in energy intake adequacy.
Seokju Kang, Youri Jin, Yongsoon Park
doaj +1 more source