Results 71 to 80 of about 906,987 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Sex differences in the association between total energy intake and all-cause mortality among patients with metabolic dysfunction-associated steatotic liver disease

Scientific Reports
The long-term association between total energy intake and clinical outcomes in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear. The present study aimed to explore the associations between total energy intake
Changsi Wang, Hongfei Ma, Hongfang Yang, Qi Nie, Lin Zhu, Jiawei Yin, Li Zhou   +6 more
doaj   +1 more source

Pengaruh asupan energi dan protein terhadap perubahan status gizi pasien anak selama dirawat di RSUP Dr. Kariadi Semarang

Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition, 2016
Background : Adequate energy and  protein  intake  for  children  patients is required as efforts to prevent decline in nutritional status during hospitalization.
Bandawati Bandawati, Maria Mexitalia, M. Zen Rahfiludin   +2 more
doaj   +1 more source

Experimental study of a counter-flow regenerative evaporative cooler [PDF]

, 2016
This paper aims to investigate the operational performance and impact factors of a counter-flow regenerative evaporative cooler (REC). This was undertaken through a dedicated experimental process.
Dong, Xuelin, Duan, Zhiyin, Zhan, Changhong, Zhao, Xudong   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Energy and Protein Intake and Its Relationship with Pulmonary Function in Chronic Obstructive Pulmonary Disease (COPD) Patients [PDF]

Acta Medica Iranica, 2010
Chronic Obstructive Pulmonary Disease (COPD) is a public health problem worldwide. Increased energy and protein needs, decreased energy and protein intake are common in COPD patients.
Leila Yazdanpanah, Farzad Shidfar, Ali Javad Moosavi, Hassan Heidarnazhad, Hamid Haghani   +4 more
doaj   +1 more source

Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain [PDF]

, 2017
BACKGROUND: Cross-sectional studies suggest that the microbes in the human gut have a role in obesity by influencing the human body's ability to extract and store calories.
A.M. Valdes, C. Menni, C.J. Steves, M.A. Jackson, T. Pallister, T.D. Spector   +5 more
core   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

An energy sensor for control of energy intake [PDF]

Proceedings of the Nutrition Society, 1997
Control of energy intake, either in response to changes in the energy content of food or in energy expenditures and storage, is based on the detection of a feedback signal generated in the processing of metabolic fuels for energy. Evidence from studies of the fructose analogue, 2,5-AM, indicates a sensor in liver responds to changes in intracellular ...
openaire   +2 more sources