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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Agreement between Two Methods of Dietary Data Collection in Male Adolescent Academy-Level Soccer Players [PDF]
Collecting accurate and reliable nutritional data from adolescent populations is challenging, with current methods providing significant under-reporting.
Stevenson, Emma +12 more
core +1 more source
Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. [PDF]
OBJECTIVE Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related ...
Nogueiras, Ruben +13 more
core +3 more sources
Play behaviour has been proposed as a measure of good welfare in growing animals and locomotor play by calves is often reduced after weaning off milk.
G.G. Miguel-Pacheco +3 more
doaj +1 more source
Background Extra energy intake is commonly recommended for pregnant women to support fetal growth. However, relevant data regarding variations in energy intake and expenditure, body mass index and gestational weight gain (GWG) are frequently not ...
Marina Minami +11 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Animal energy intake and expenditure strategies in response to environmental fluctuations have been widely studied. Optimal foraging theory (OFT) is the dominant framework in this field; however, studies addressing the OFT in endangered waterbird species
Chao Yu +7 more
doaj +1 more source
Background : Adequate energy and protein intake for children patients is required as efforts to prevent decline in nutritional status during hospitalization.
Bandawati Bandawati +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Idle Operation with Low Intake Valve Lift in a Port Fuel Injected Engine [PDF]
Reducing fuel consumption is a prime objective in the automotive industry in order to meet regulatory and customer demands. Variable valve actuation offers many opportunities for improving the spark ignition engine’s performance in areas such as fuel ...
CLENCI, Adrian +12 more
core +1 more source

