Results 81 to 90 of about 906,987 (311)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2004 OBJECTIVES: The energy density (ED) of the diet is considered an important determinant of total energy intake and thus energy balance and weight change.
Cameron-Smith, D +4 more
core +1 more source
Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults [PDF]
, 2011 It is generally assumed that a FFQ is not suitable to estimate the absolute levels of individual energy intake. However, in epidemiological studies, reported nutrients by FFQ are often corrected for this intake.
Geelen, A. +2 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Macronutrients, Appetite, and Energy Intake [PDF]
Annual Review of Nutrition, 2016 Each of the macronutrients—carbohydrate, protein, and fat—has a unique set of properties that influences health, but all are a source of energy. The optimal balance of their contribution to the diet has been a long-standing matter of debate. Over the past half century, thinking has progressed regarding the mechanisms by which each macronutrient may ...
Alicia L, Carreiro +9 more
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Jurnal Gizi Klinik Indonesia, 2005 Background: The main problem facing Indonesian people today is nutrition deficiency which brings effect to low quality of human resources. Infants aging 6 – 12 months are at high risk of having growth and development disorder. Complementary breastfeeding
Antoni Herwan +2 more
doaj +1 more source
Media Gizi Indonesia, 2020 Nutrition college students as a representatives in society is required to have ideal and healthy body. Besides aff ected by those demands, body image is also aff ected by nutritional status and energy intake.
Alifatuz Zahrah, Lailatul Muniroh
doaj +1 more source
Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]
, 2016 Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb +14 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source