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Physicochemical characterisation of dihydro-alpha-lipoic acid interaction with human serum albumin by multi-spectroscopic and molecular modelling approaches [PDF]
Journal of the Serbian Chemical Society, 2021 The binding of a popular food supplement and well-known antioxidant, dihydro-alpha-lipoic acid (DHLA) to human serum albumin (HSA) was characterised. The binding was monitored by several spectroscopic methods together with the molecular docking approach.
Gligorijević Nikola +5 more
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Cardiac Energy Metabolism in Heart Failure
Circulation Research, 2021 Alterations in cardiac energy metabolism contribute to the severity of heart failure. However, the energy metabolic changes that occur in heart failure are complex and are dependent not only on the severity and type of heart failure present but also on ...
G. Lopaschuk +4 more
semanticscholar +1 more source
Chemerin: A Functional Adipokine in Reproductive Health and Diseases
Biomedicines, 2022 As a multifaceted adipokine, chemerin has been found to perform functions vital for immunity, adiposity, and metabolism through its three known receptors (chemokine-like receptor 1, CMKLR1; G-protein-coupled receptor 1, GPR1; C-C motif chemokine receptor-
Ming Yu +9 more
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Astrocytes as Key Regulators of Brain Energy Metabolism: New Therapeutic Perspectives
Frontiers in Physiology, 2022 Astrocytes play key roles in the regulation of brain energy metabolism, which has a major impact on brain functions, including memory, neuroprotection, resistance to oxidative stress and homeostatic tone.
Elidie Béard +4 more
semanticscholar +1 more source
The Insulin-like Growth Factor System and Colorectal Cancer
Life, 2022 Insulin-like growth factors (IGFs) are peptides which exert mitogenic, endocrine and cytokine activities. Together with their receptors, binding proteins and associated molecules, they participate in numerous pathophysiological processes, including ...
Nikola Gligorijević +7 more
doaj +1 more source
Cell & Bioscience, 2023 Background Metabolic homeostasis is closely related to early impairment of cell fate determination and embryo development. The protein kinase mechanistic target of rapamycin (mTOR) is a key regulator of cellular metabolism in the body. Inhibition of mTOR
Chiyuan Ma +17 more
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Biomolecules, 2021 Depression affects the reproductive axis at the hypothalamus and pituitary levels, which has a significant impact on female fertility. It has been reported that G protein-coupled receptor 1 (Gpr1) mRNA is expressed in both the hypothalamus and ovaries ...
Rongrong Li +11 more
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Emerging Roles of Energy Metabolism in Ferroptosis Regulation of Tumor Cells
Advancement of science, 2021 Ferroptosis is a new form of regulated cell death, which is characterized by the iron‐dependent accumulation of lethal lipid peroxides and involved in many critical diseases.
Xuemei Yao +6 more
semanticscholar +1 more source
Foods, 2022 The Brazil nut (BN) is a promising food due to its numerous health benefits, but it is still necessary to systematically review the scientific evidence on these benefits. Thus, we examined the effects of regular BN consumption on health markers in humans
Alessandra da Silva +4 more
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Science Advances, 2021 Drosophila is a useful model system to study the regulation of energy metabolism and its diseases like obesity and diabetes. The organs and metabolic pathways involved in energy metabolism, and the process of ATP production from nutrients, are comparable
Nirmalya Chatterjee, N. Perrimon
semanticscholar +1 more source