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Rethinking Human Energy Metabolism [PDF]
For a long time, glycolysis and mitochondrial oxidative phosphorylation were opposed to each other. Glycolysis works when there is a lack of oxygen; the mitochondria supply ATP in an oxygen environment.
Alexander Panov +4 more
doaj +2 more sources
Energy Metabolism and Diet [PDF]
Energy metabolism at whole body and cellular, and even organelle (i [...]
Nieuwenhuizen, Arie G. +1 more
openaire +3 more sources
Chemerin: A Functional Adipokine in Reproductive Health and Diseases
As a multifaceted adipokine, chemerin has been found to perform functions vital for immunity, adiposity, and metabolism through its three known receptors (chemokine-like receptor 1, CMKLR1; G-protein-coupled receptor 1, GPR1; C-C motif chemokine receptor-
Ming Yu +9 more
doaj +1 more source
The Insulin-like Growth Factor System and Colorectal Cancer
Insulin-like growth factors (IGFs) are peptides which exert mitogenic, endocrine and cytokine activities. Together with their receptors, binding proteins and associated molecules, they participate in numerous pathophysiological processes, including ...
Nikola Gligorijević +7 more
doaj +1 more source
Background Metabolic homeostasis is closely related to early impairment of cell fate determination and embryo development. The protein kinase mechanistic target of rapamycin (mTOR) is a key regulator of cellular metabolism in the body. Inhibition of mTOR
Chiyuan Ma +17 more
doaj +1 more source
Physicochemical characterisation of dihydro-alpha-lipoic acid interaction with human serum albumin by multi-spectroscopic and molecular modelling approaches [PDF]
The binding of a popular food supplement and well-known antioxidant, dihydro-alpha-lipoic acid (DHLA) to human serum albumin (HSA) was characterised. The binding was monitored by several spectroscopic methods together with the molecular docking approach.
Gligorijević Nikola +5 more
doaj +1 more source
Depression affects the reproductive axis at the hypothalamus and pituitary levels, which has a significant impact on female fertility. It has been reported that G protein-coupled receptor 1 (Gpr1) mRNA is expressed in both the hypothalamus and ovaries ...
Rongrong Li +11 more
doaj +1 more source
The Brazil nut (BN) is a promising food due to its numerous health benefits, but it is still necessary to systematically review the scientific evidence on these benefits. Thus, we examined the effects of regular BN consumption on health markers in humans
Alessandra da Silva +4 more
doaj +1 more source
Background Most NSCLCs metastasised out of the lungs at the time of diagnosis and cannot be surgically removed . Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with NSCLC without EGFR, ALK, and ROS ...
Qing Xia +12 more
doaj +1 more source
Small intestinal microbiota composition altered in obesity-T2DM mice with high salt fed
Obesity has become a global concern because of increasing the risk of many diseases. Alterations in human gut microbiota have been proven to be associated with obesity, yet the mechanism of how the microbiota are altered by high salt diet (HSD) remains ...
Goher Kerem +9 more
doaj +1 more source

