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Chemerin: A Functional Adipokine in Reproductive Health and Diseases
Biomedicines, 2022 As a multifaceted adipokine, chemerin has been found to perform functions vital for immunity, adiposity, and metabolism through its three known receptors (chemokine-like receptor 1, CMKLR1; G-protein-coupled receptor 1, GPR1; C-C motif chemokine receptor-
Ming Yu +9 more
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The Insulin-like Growth Factor System and Colorectal Cancer
Life, 2022 Insulin-like growth factors (IGFs) are peptides which exert mitogenic, endocrine and cytokine activities. Together with their receptors, binding proteins and associated molecules, they participate in numerous pathophysiological processes, including ...
Nikola Gligorijević +7 more
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Physicochemical characterisation of dihydro-alpha-lipoic acid interaction with human serum albumin by multi-spectroscopic and molecular modelling approaches [PDF]
Journal of the Serbian Chemical Society, 2021 The binding of a popular food supplement and well-known antioxidant, dihydro-alpha-lipoic acid (DHLA) to human serum albumin (HSA) was characterised. The binding was monitored by several spectroscopic methods together with the molecular docking approach.
Gligorijević Nikola +5 more
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Cell & Bioscience, 2023 Background Metabolic homeostasis is closely related to early impairment of cell fate determination and embryo development. The protein kinase mechanistic target of rapamycin (mTOR) is a key regulator of cellular metabolism in the body. Inhibition of mTOR
Chiyuan Ma +17 more
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Biomolecules, 2021 Depression affects the reproductive axis at the hypothalamus and pituitary levels, which has a significant impact on female fertility. It has been reported that G protein-coupled receptor 1 (Gpr1) mRNA is expressed in both the hypothalamus and ovaries ...
Rongrong Li +11 more
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The influence of shc proteins and aging on whole body energy expenditure and substrate utilization in mice. [PDF]
, 2012 While it has been proposed that Shc family of adaptor proteins may influence aging by regulating insulin signaling and energy metabolism, the overall impact of Shc proteins on whole body energy metabolism has yet to be elucidated.
Kim, Kyoungmi +2 more
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Foods, 2022 The Brazil nut (BN) is a promising food due to its numerous health benefits, but it is still necessary to systematically review the scientific evidence on these benefits. Thus, we examined the effects of regular BN consumption on health markers in humans
Alessandra da Silva +4 more
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BMC Cancer, 2021 Background Most NSCLCs metastasised out of the lungs at the time of diagnosis and cannot be surgically removed . Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with NSCLC without EGFR, ALK, and ROS ...
Qing Xia +12 more
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Small intestinal microbiota composition altered in obesity-T2DM mice with high salt fed
Scientific Reports, 2023 Obesity has become a global concern because of increasing the risk of many diseases. Alterations in human gut microbiota have been proven to be associated with obesity, yet the mechanism of how the microbiota are altered by high salt diet (HSD) remains ...
Goher Kerem +9 more
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Methane mitigation potential of phyto-sources from Northeast India and their effect on rumen fermentation characteristics and protozoa in vitro [PDF]
Veterinary World, 2018 Aim: The aim of the study was to explore the anti-methanogenic potential of phyto-sources from Northeast region of the country and assess the effect on rumen fermentation characteristics and protozoa for their likely inclusion in animal diet to reduce ...
Luna Baruah +4 more
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