Results 131 to 140 of about 8,597,032 (385)

Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory

open access: yesNature Communications, 2017
Efficient energy use has constrained the evolution of nervous systems. However, it is unresolved whether energy metabolism may resultantly regulate major brain functions. Our observation that Drosophila flies double their sucrose intake at an early stage
P. Plaçais   +7 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Publisher Correction: Small intestinal microbiota composition altered in obesity-T2DM mice with high salt fed

open access: yesScientific Reports, 2023
Goher Kerem   +9 more
doaj   +1 more source

Skeletal muscle energy metabolism during exercise

open access: yesNature Metabolism, 2020
M. Hargreaves, L. Spriet
semanticscholar   +1 more source

Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery

open access: yesmBio, 2017
Drug-resistant mycobacterial infections are a serious global health challenge, leading to high mortality and socioeconomic burdens in developing countries worldwide.
D. Bald   +3 more
semanticscholar   +1 more source

Purification and characterization of a thermophilic NAD+‐dependent lactate dehydrogenase from Moorella thermoacetica

open access: yesFEBS Open Bio, EarlyView.
The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley   +1 more source

Peptide drugs application in metabolic diseases and discovery strategies

open access: yesJournal of Holistic Integrative Pharmacy, 2022
Peptides (or polypeptides) are generally defined as those molecules compounded with less than 100 amino acids linked by peptide bonds, and the relative molecular weight is less than 10 000 Da usually. To date, more than 7 000 naturally peptides have been
Bin TENG, Junfeng LI, Peigen REN
doaj  

Metabolic energy expenditure for time-varying isometric forces [PDF]

open access: yesarXiv
Muscles consume metabolic energy (ATP) to produce force. A mathematical model for energy expenditure can be useful in estimating real-time costs of movements or to predict energy optimal movements. Metabolic cost models developed so far have predominantly aimed at dynamic movement tasks, where mechanical work dominates.
arxiv  

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