Results 61 to 70 of about 7,366,329 (309)

Conceptualizing household energy metabolism : a methodological contribution [PDF]

, 2019
CITATION: Strydom, A., Musango, J. K. & Currie, P. K. 2019. Conceptualizing household energy metabolism : a methodological contribution. Energies, 12(21):4125, doi:10.3390/en12214125.The original publication is available at https://www.mdpi ...
Currie, Paul K., Paul K. Currie, Adél Strydom, Josephine Kaviti Musango, Musango, Josephine Kaviti, Strydom, Adel   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Aspects of the respiratory metabolism of juvenile rainbow trout (Oncorhynchus mykiss) at sustained swimming speeds [PDF]

, 1993
Bibliography: leaves 98-111.A detailed description of the design of an apparatus suitable for investigations into the respiratory physiology of small nektonic organisms at various swimming speeds is presented. Juvenile rainbow trout (Oncorhynchus mykiss)
Durholtz, Deon
core   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science
Meiosis is essential for sexual reproduction, yet the impact of microgravity on oocyte maturation remains unclear, raising concerns for reproductive success in space environments.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Effects of Intermittent Fasting on Cardiometabolic Health: An Energy Metabolism Perspective

, 2022
This review summarizes the effects of different types of intermittent fasting (IF) on human cardiometabolic health, with a focus on energy metabolism.
Eric Ravussin, Manuel Dote-Montero, Guillermo Sanchez-Delgado   +2 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment

Journal of Advanced Research
Introduction: Embryo implantation requires synergistic interaction between the embryo and the receptive endometrium. Glycoproteins and glycan-binding proteins are involved in endometrium-embryo attachment.
Xinyue Dong, Hao Wang, Jinxuan Cai, Yichun Wang, Dezhi Chai, Zichen Sun, Jie Chen, Mengxia Li, Tianxia Xiao, Chunhua Shan, Jian V. Zhang, Ming Yu   +11 more
doaj   +1 more source

Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling

Scientific Reports, 2018
Mitochondrial dysfunction is usually associated with various metabolic disorders and ageing. However, salutary effects in response to mild mitochondrial perturbations have been reported in multiple organisms, whereas molecular regulators of cell ...
Verena Coleman, Piangkwan Sa-Nguanmoo, Jeannette Koenig, Tim J. Schulz, Tilman Grune, Susanne Klaus, Anna P. Kipp, Mario Ost   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source