Results 41 to 50 of about 465,067 (266)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Rapid and stable calcium-looping solar thermochemical energy storage via co-doping binary sulfate and Al–Mn–Fe oxides

open access: yesGreen Energy & Environment
Solar thermochemical energy storage based on calcium looping (CaL) process is a promising technology for next-generation concentrated solar power (CSP) systems.
Changjian Yuan   +10 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigating interfacial cracks in bi-materials through a 4-point bending model analysis [PDF]

open access: yesTheoretical and Applied Mechanics
This study focuses on examining the failure behavior of interfacial cracks in bimaterial structures. Bimaterials present a unique challenge due to their composition, consisting of two materials that can be homogeneous and isotropic, with a specific ...
Mankour Abdeljelil, Belabbes Bachir B.
doaj   +1 more source

Numerical study of critical straight, frown, and chevron incisions in small incision cataract surgery

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction: When an intraocular lens (IOL) injector is inserted through a pre-cut corneal incision (e.g., an empirical size of 2.2 mm) during small incision cataract surgery, uncontrollable tearing to the corneal tissue may occur, which is highly ...
Yang Han, Yang Han, Nan Qi, Nan Qi
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research on the energy evolution characteristics and the failure intensity of rocks

open access: yesInternational Journal of Mining Science and Technology, 2020
It is pretty challenging and difficult to quantitatively evaluate the intensity of dynamic disasters in deep mining engineering. Based on the uniaxial loading-unloading experiments for five types of rocks, this paper investigated the energy evolution ...
Lin Gao   +3 more
doaj   +1 more source

Estimations of Critical Clear Corneal Incisions Required for Lens Insertion in Cataract Surgery: A Mathematical Aspect

open access: yesFrontiers in Physiology, 2022
In a routine cataract operation cornea tissue may be damaged when an intra-ocular lens (IOL) injector of diameter between 1.467 and 2.011 mm is inserted through an empirically designed 2.2 mm corneal incision.
Nan Qi   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Young’s Modulus and Hardness Identification of Extruded Aluminum by Scratching Damper

open access: yesMachines
A special vibration damper is proposed for Young’s modulus and hardness identification through a scratching process on extruded aluminum. This paper presents the design and working principle of a scratching damper based on a scratching device.
Chun-Nam Wong   +3 more
doaj   +1 more source

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