Results 61 to 70 of about 1,654,839 (351)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Estimations of Critical Clear Corneal Incisions Required for Lens Insertion in Cataract Surgery: A Mathematical Aspect

Frontiers in Physiology, 2022
In a routine cataract operation cornea tissue may be damaged when an intra-ocular lens (IOL) injector of diameter between 1.467 and 2.011 mm is inserted through an empirically designed 2.2 mm corneal incision.
Nan Qi, David Lockington, Lei Wang, Kanna Ramaesh, Xiaoyu Luo   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Young’s Modulus and Hardness Identification of Extruded Aluminum by Scratching Damper

Machines
A special vibration damper is proposed for Young’s modulus and hardness identification through a scratching process on extruded aluminum. This paper presents the design and working principle of a scratching damper based on a scratching device.
Chun-Nam Wong, Anand Vyas, Wai-On Wong, Ruqi Sun   +3 more
doaj   +1 more source

Anisotropic fragmentation in low-energy dissociative recombination [PDF]

, 2008
On a dense energy grid reaching up to 75 meV electron collision energy the fragmentation angle and the kinetic energy release of neutral dissociative recombination fragments have been studied in a twin merged beam experiment.
A Petrignani, A S Jaroshevich, A Wolf, B Jordon-Thaden, Bardsley J N, C Krantz, D A Orlov, D Schwalm, D Shafir, D Zajfman, F O Waffeu Tamo, F O Waffeu Tamo, H Buhr, H Rubinstein, I F Schneider, J Hoffmann, M B Mendes, M Froese, M Grieser, M H Berg, M Lange, M Lestinsky, O Novotný, Orlov D A, S Novotny, Schneider I F, Shafir D, Takagi H   +27 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Experimental investigation of CFRP fracture toughness by delamination type

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2021
The results of analyzing fracture toughness in carbon fiber-reinforced plastics by the type of delamination are presented in the article. The goal of this paper is investigation of delamination propagation process and fracture mechanics parameters in ...
S. A. Chernyakin
doaj   +1 more source

Energy Release Rates for Various Defects

, 1983
It is known that the energy-release rates associated with translation, rotation, and self-similar expansion of cavities or cracks in solids are expressed by path-independent integrals J, L and M, respectively. These integrals are of interest to NDE in that they can be used to characterize nondestructively defects in solids.
Pak, Eugene, Golebiewska-Herrmann, Alicia, Herrmann, George   +2 more
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Investigating interfacial cracks in bi-materials through a 4-point bending model analysis [PDF]

Theoretical and Applied Mechanics
This study focuses on examining the failure behavior of interfacial cracks in bimaterial structures. Bimaterials present a unique challenge due to their composition, consisting of two materials that can be homogeneous and isotropic, with a specific ...
Mankour Abdeljelil, Belabbes Bachir B.
doaj   +1 more source