Results 111 to 120 of about 3,743,775 (372)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A Multidimensional Benchmark of Public EEG Datasets for Driver State Monitoring in Brain–Computer Interfaces

Sensors
Electroencephalography (EEG)-based brain-computer interfaces (BCIs) hold significant potential for enhancing driver safety through real-time monitoring of cognitive and affective states.
Sirine Ammar, Nesrine Triki, Mohamed Karray, Mohamed Ksantini   +3 more
doaj   +1 more source

Ultra‐Efficient and Broadband Nonlinear AlGaAs‐on‐Insulator Chip for Low‐Power Optical Signal Processing

Laser & Photonics reviews, 2018
Four‐wave mixing (FWM) is a versatile optical nonlinear parametric process that enables a plethora of signal processing functionalities in optical communication.
M. Pu, Hao Hu, L. Ottaviano, E. Semenova, D. Vukovic, L. Oxenløwe, K. Yvind   +6 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A Low-Rank Matrix Recovery Approach for Energy Efficient EEG Acquisition for a Wireless Body Area Network

Sensors, 2014
We address the problem of acquiring and transmitting EEG signals in Wireless Body Area Networks (WBAN) in an energy efficient fashion. In WBANs, the energy is consumed by three operations: sensing (sampling), processing and transmission. Previous studies
Angshul Majumdar, Anupriya Gogna, Rabab Ward   +2 more
doaj   +1 more source

Development of Energy-Efficient Biomedical Signal Processing Circuits

The rapid advancement of biomedical technologies has necessitated the development of energy-efficient signal processing circuits, particularly in portable and wearable medical devices. This paper explores the design and implementation of such circuits, focusing on the processing of critical biomedical signals, including electrocardiograms (ECG ...
Owen Graham, Mark Sharp
openaire   +1 more source

Improving Event-Based Non-Intrusive Load Monitoring Using Graph Signal Processing

IEEE Access, 2018
Large-scale smart energy metering deployment worldwide and integration of smart meters within the smart grid will enable two-way communication between the consumer and energy network, thus ensuring improved response to demand.
Bochao Zhao, Kanghang He, L. Stanković, V. Stanković   +3 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Use of the shearlet energy entropy and of the support vector machine classifier to process weak microseismic and desert seismic signals [PDF]

, 2020
Yue Li, Shiyu Fan, Chao Zhang, Baojun Yang   +3 more
openalex   +1 more source